Examining diabetic heel ulcers through an ecological lens: microbial community dynamics associated with healing and infection
TJ Sloan, JC Turton, J Tyson… - Journal of medical …, 2019 - microbiologyresearch.org
Purpose. While some micro-organisms, such as Staphylococcus aureus, are clearly
implicated in causing tissue damage in diabetic foot ulcers (DFUs), our knowledge of the …
implicated in causing tissue damage in diabetic foot ulcers (DFUs), our knowledge of the …
The neuropathic diabetic foot ulcer microbiome is associated with clinical factors
Nonhealing diabetic foot ulcers (DFUs) are a common and costly complication of diabetes.
Microbial burden, or “bioburden,” is believed to underlie delayed healing, although little is …
Microbial burden, or “bioburden,” is believed to underlie delayed healing, although little is …
[HTML][HTML] The dynamic wound microbiome
Abstract Background Diabetic foot ulcers (DFUs) account for the majority of all limb
amputations and hospitalizations due to diabetes complications. With 30 million cases of …
amputations and hospitalizations due to diabetes complications. With 30 million cases of …
Microbial community distribution and core microbiome in successive wound grades of individuals with diabetic foot ulcers
A Jnana, V Muthuraman, VK Varghese… - Applied and …, 2020 - Am Soc Microbiol
Diabetic foot ulcer (DFU) is a major complication of diabetes with high morbidity and
mortality rates. The pathogenesis of DFUs is governed by a complex milieu of environmental …
mortality rates. The pathogenesis of DFUs is governed by a complex milieu of environmental …
[PDF][PDF] Strain-and species-level variation in the microbiome of diabetic wounds is associated with clinical outcomes and therapeutic efficacy
Chronic wounds are a major complication of diabetes associated with high morbidity and
health care expenditures. To investigate the role of colonizing microbiota in diabetic wound …
health care expenditures. To investigate the role of colonizing microbiota in diabetic wound …
[HTML][HTML] One step closer to understanding the role of bacteria in diabetic foot ulcers: characterising the microbiome of ulcers
K Smith, A Collier, EM Townsend, LE O'Donnell… - BMC microbiology, 2016 - Springer
Background The aim of this study was to characterise the microbiome of new and recurrent
diabetic foot ulcers using 16S amplicon sequencing (16S AS), allowing the identification of a …
diabetic foot ulcers using 16S amplicon sequencing (16S AS), allowing the identification of a …
[HTML][HTML] Microbiome characterization of infected diabetic foot ulcers in association with clinical outcomes: traditional cultures versus molecular sequencing methods
Background Infected diabetic foot ulcers (IDFU) are a major complication of diabetes
mellitus. These potentially limb-threatening ulcers are challenging to treat due to impaired …
mellitus. These potentially limb-threatening ulcers are challenging to treat due to impaired …
[HTML][HTML] Exploring the microbiota of diabetic foot infections with culturomics
J Jneid, N Cassir, S Schuldiner, N Jourdan… - Frontiers in cellular …, 2018 - frontiersin.org
The purpose of this prospective observational study was to evaluate the richness and
diversity of bacteria in samples from diabetic foot infections using a culturomics approach …
diversity of bacteria in samples from diabetic foot infections using a culturomics approach …
[HTML][HTML] The microbiome of diabetic foot ulcers: a comparison of swab and tissue biopsy wound sampling techniques using 16S rRNA gene sequencing
Background Health-care professionals need to collect wound samples to identify potential
pathogens that contribute to wound infection. Obtaining appropriate samples from diabetic …
pathogens that contribute to wound infection. Obtaining appropriate samples from diabetic …
[HTML][HTML] Next generation DNA sequencing of tissues from infected diabetic foot ulcers
M Malone, K Johani, SO Jensen, IB Gosbell… - …, 2017 - thelancet.com
We used next generation DNA sequencing to profile the microbiome of infected Diabetic
Foot Ulcers (DFUs). The microbiota was correlated to clinical parameters and treatment …
Foot Ulcers (DFUs). The microbiota was correlated to clinical parameters and treatment …