DNA methylation aberrant in atherosclerosis

Y Dai, D Chen, T Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
Atherosclerosis (AS) is a pathological process involving lipid oxidation, immune system
activation, and endothelial dysfunction. The activated immune system could lead to …

DNA methylation in atherosclerosis: a new perspective

Y Zhang, J Mei, J Li, Y Zhang… - Evidence‐Based …, 2021 - Wiley Online Library
Atherosclerotic cardiovascular diseases, in which atherosclerosis (AS) is the main
pathologic basis, are currently the primary diseases leading to human deaths. Emerging …

DNA methylation abnormalities in atherosclerosis

S Tabaei, SS Tabaee - Artificial cells, nanomedicine, and …, 2019 - Taylor & Francis
Atherosclerosis is a complex disease with involvement of intermediate-, large-sized arteries.
Atherosclerosis is characterized by the accumulation of vascular lipids, immune system …

DNA methylation and histone post-translational modifications in atherosclerosis and a novel perspective for epigenetic therapy

L Zhang, C Xia, Y Yang, F Sun, Y Zhang… - Cell Communication and …, 2023 - Springer
Atherosclerosis, which is a vascular pathology characterized by inflammation and plaque
build-up within arterial vessel walls, acts as the important cause of most cardiovascular …

Histone methylation related therapeutic challenge in cardiovascular diseases

Y Yang, Y Luan, RX Yuan, Y Luan - Frontiers in Cardiovascular …, 2021 - frontiersin.org
The epidemic of cardiovascular diseases (CVDs) is predicted to spread rapidly in advanced
countries accompanied by the high prevalence of risk factors. In terms of pathogenesis, the …

Role of DNA methylation in cardiovascular diseases

Y Zhang, C Zeng - Clinical and experimental hypertension, 2016 - Taylor & Francis
ABSTRACT A complex interplay between genetic and environmental factors is involved in
the pathogenesis of cardiovascular diseases (CVDs). Environmental factors have crucial …

Potential epigenetic therapeutics for atherosclerosis treatment

I Nicorescu, GM Dallinga, MPJ de Winther, ESG Stroes… - Atherosclerosis, 2019 - Elsevier
Notwithstanding the intense efforts into the understanding and prevention of cardiovascular
disease (CVD), its complex pathology remains the leading cause of mortality worldwide. The …

Aberrant DNA methylation in the pathogenesis of atherosclerosis

Z Hai, W Zuo - Clinica Chimica Acta, 2016 - Elsevier
Atherosclerosis, a multifactorial disease of large-and intermediate-sized arteries, is
characterized by the accumulation of lipids and the proliferation of arterial smooth muscle …

DNA methylation processes in atherosclerotic plaque

E Aavik, M Babu, S Ylä-Herttuala - Atherosclerosis, 2019 - Elsevier
Underlying mechanisms of cardiovascular diseases (CVD) have been investigated for over
100 years and novel molecular level mechanisms in the pathophysiology are still …

Epigenetic regulation in pathology of atherosclerosis: a novel perspective

H Tang, Z Zeng, C Shang, Q Li, J Liu - Frontiers in Genetics, 2021 - frontiersin.org
Atherosclerosis, characterized by atherosclerotic plaques, is a complex pathological process
that involves different cell types and can be seen as a chronic inflammatory disease. In the …