Background: More elderly patients are being treated with chemotherapy. Reliable and
accurate measures of renal function are needed to obtain predictable, safe and effective …

Background Kidney function assessment by estimated glomerular filtration rate (eGFR)
equations, such as the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) …

Purpose Alterations in renal clearance of anticancer drugs can affect the occurrence of
toxicities related to drug exposure. The National Cancer Institute and the US Food and Drug …

Abstract BACKGROUND. The Renal Insufficiency and Cancer Medications (IRMA) study is a
French national observational study. The results from this study of nearly 5000 patients …

The accuracy of the estimated glomerular filtration rate (eGFR) in cancer patients is very
important for dose adjustments of anti-malignancy drugs to reduce toxicities and enhance …

Renal insufficiency has been shown to be highly prevalent in patients with cancer. This renal
insufficiency has been reported to be associated with reduced overall survival and …

The frequent need to obtain an estimate of renal function in cancer patients, not least for
targeting carboplatin dose, has led to a number of approaches to estimate glomerular …

Objective: To assess the prevalence of renal insufficiency (RI) in cancer patients, as well as
describe the profile of anticancer drugs prescribed, need for dose adjustment, and potential …

Background: Cytotoxic agents have a narrow therapeutic window. A high percentage of
some of them is renally excreted in unchanged form. Accurate assessment of an individual's …

Background The aim of this study was to compare measured glomerular filtration rate (GFR)
with estimates of GFR derived from the population pharmacokinetic methods of Martin and …