Beyond the sleep-amyloid interactions in Alzheimer's disease pathogenesis
Cognitive impairment in older adults is associated with sleep and circadian rhythm
disturbances. Numerous studies have linked disrupted sleep and circadian rhythms with …
disturbances. Numerous studies have linked disrupted sleep and circadian rhythms with …
Bidirectional relationship between sleep and Alzheimer's disease: role of amyloid, tau, and other factors
C Wang, DM Holtzman - Neuropsychopharmacology, 2020 - nature.com
As we age, we experience changes in our nighttime sleep and daytime wakefulness.
Individuals afflicted with Alzheimer's disease (AD) can develop sleep problems even before …
Individuals afflicted with Alzheimer's disease (AD) can develop sleep problems even before …
[HTML][HTML] Sleep in Alzheimer's disease–beyond amyloid
JK Holth, TK Patel, DM Holtzman - Neurobiology of sleep and circadian …, 2017 - Elsevier
Sleep disorders are prevalent in Alzheimer's disease (AD) and a major cause of
institutionalization. Like AD pathology, sleep abnormalities can appear years before …
institutionalization. Like AD pathology, sleep abnormalities can appear years before …
[HTML][HTML] It's complicated: The relationship between sleep and Alzheimer's disease in humans
BP Lucey - Neurobiology of disease, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by an
asymptomatic period of amyloid-β (Aβ) deposition as insoluble extracellular plaque …
asymptomatic period of amyloid-β (Aβ) deposition as insoluble extracellular plaque …
Circadian and sleep dysfunction in Alzheimer's disease
MS Uddin, D Tewari, A Al Mamun, MT Kabir… - Ageing Research …, 2020 - Elsevier
Alzheimer's disease (AD) is a devastating and irreversible cognitive impairment and the
most common type of dementia. Along with progressive cognitive impairment, dysfunction of …
most common type of dementia. Along with progressive cognitive impairment, dysfunction of …
Sleep–wake regulation and the hallmarks of the pathogenesis of Alzheimer's disease
M Van Egroo, J Narbutas, D Chylinski… - Sleep, 2019 - academic.oup.com
While efficient treatments for Alzheimer's disease (AD) remain elusive, a growing body of
research has highlighted sleep–wake regulation as a potential modifiable factor to delay …
research has highlighted sleep–wake regulation as a potential modifiable factor to delay …
The sleep side of aging and Alzheimer's disease
As we age, sleep patterns undergo significant modifications in micro and macrostructure,
worsening cognition and quality of life. These are associated with remarkable brain …
worsening cognition and quality of life. These are associated with remarkable brain …
[HTML][HTML] Amyloid-β diurnal pattern: possible role of sleep in Alzheimer's disease pathogenesis
BP Lucey, RJ Bateman - Neurobiology of aging, 2014 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
cognitive decline that is a growing public health crisis with a prevalence projected to more …
cognitive decline that is a growing public health crisis with a prevalence projected to more …
[PDF][PDF] Unraveling the Mechanisms Underlying Disordered Sleep in Alzheimer's Disease
R Luke, I Alymova - The Journal of Neuroscience, 2023 - Soc Neuroscience
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the aggregation
of b-amyloid and tau. While cognitive impairment is the primary clinical manifestation of AD …
of b-amyloid and tau. While cognitive impairment is the primary clinical manifestation of AD …
Sleep as a potential biomarker of tau and β-amyloid burden in the human brain
Recent proposals suggest that sleep may be a factor associated with accumulation of two
core pathological features of Alzheimer's disease (AD): tau and β-amyloid (Aβ). Here we …
core pathological features of Alzheimer's disease (AD): tau and β-amyloid (Aβ). Here we …