Combination antiretroviral therapy (ART) can block multiple stages of the HIV-1 life cycle to
prevent progression to AIDS in people living with HIV-1. However, owing to the persistence …

Effective antiretroviral therapy (ART) blunts viraemia, which enables HIV-1-infected
individuals to control infection and live long, productive lives. However, HIV-1 infection …

Antiretroviral therapy (ART) is able to suppress HIV-1 replication indefinitely in individuals
who have access to these medications, are able to tolerate these drugs, and are motivated …

Antiretroviral therapy can effectively block HIV-1 replication and prevent or reverse
immunodeficiency in HIV-1-infected individuals. However, viral replication resumes within …

Highly active antiretroviral therapy (HAART) suppresses HIV-1 replication, transforming the
outlook for infected patients. However, reservoirs of replication-competent forms of the virus …

The treatment of AIDS with combination antiretroviral therapy (cART) remains lifelong largely
because the virus persists in latent reservoirs. Elimination of latently infected cells could …

Combination antiretroviral therapy (ART) to treat human immunodeficiency virus (HIV)
infection has proven remarkably successful–for those who can access and afford it–yet HIV …

The presence of persistent, latent HIV reservoirs in CD4+ T cells obstructs current efforts to
cure infection. The so-called kick-and-kill paradigm proposes to purge these reservoirs by …

HIV is difficult to eradicate due to the persistence of a long-lived reservoir of latently infected
cells. Previous studies have shown that natural killer cells are important to inhibiting HIV …

Dendritic cells (DCs) are professional antigen-presenting cells that link innate and adaptive
immunity and are critical for the induction of protective immune responses against …