[PDF][PDF] Breviscapine alleviates NASH by inhibiting TGF‐β‐activated kinase 1‐dependent signaling

T Lan, S Jiang, J Zhang, Q Weng, Y Yu, H Li… - …, 2022 - Wiley Online Library
Background and Aims NAFLD is a key component of metabolic syndrome, ranging from
nonalcoholic fatty liver to NASH, and is now becoming the leading cause of cirrhosis and …

[HTML][HTML] Baicalin attenuates diet induced nonalcoholic steatohepatitis by inhibiting inflammation and oxidative stress via suppressing JNK signaling pathways

X Zhong, H Liu - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Nonalcoholic steatohepatitis may develop into hepatic cirrhosis. The therapeutic drugs for
NASH are absent. Baicalin (BC) has hepatoprotective effect, while whether BC could …

Baicalin improved hepatic injury of NASH by regulating NRF2/HO-1/NRLP3 pathway

H Shi, F Qiao, W Lu, K Huang, Y Wen, L Ye… - European journal of …, 2022 - Elsevier
Being at the important pathological stage and the critical treatment period of non-alcoholic
fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH) which is associated with …

Baicalin ameliorates high fat diet‐induced nonalcoholic fatty liver disease in mice via adenosine monophosphate‐activated protein kinase‐mediated regulation of …

Y Gao, J Liu, Z Hao, N Sun, J Guo… - Phytotherapy …, 2023 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disease around the
world, imposing severe threats on human health. Unfortunately, no clinically approved drugs …

[HTML][HTML] Development of a novel human triculture model of non-alcoholic fatty liver disease and identification of berberine as ameliorating steatosis, oxidative stress …

H Rafiei, M Yeung, S Kowalski, G Krystal… - Frontiers in …, 2023 - frontiersin.org
Objectives: Non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic
steatohepatitis (NASH) and hepatocarcinoma is a serious and growing problem. However …

Physalin B ameliorates nonalcoholic steatohepatitis by stimulating autophagy and NRF2 activation mediated improvement in oxidative stress

M Zhang, J Li, X Zhu, Y Zhang, S Ye, Y Leng… - Free Radical Biology …, 2021 - Elsevier
Non-alcoholic steatohepatitis (NASH) is the progressive stage of non-alcoholic fatty liver
disease that may ultimately lead to cirrhosis and liver cancer, and there are few therapeutic …

[HTML][HTML] 4-Acetylantroquinonol B ameliorates nonalcoholic steatohepatitis by suppression of ER stress and NLRP3 inflammasome activation

IC Yen, QW Tu, TC Chang, PH Lin, YF Li… - Biomedicine & …, 2021 - Elsevier
Objective Nonalcoholic fatty liver disease (NAFLD) is an inflammatory lipotoxic disorder with
a prevalence of over 25% worldwide. However, safe and effective therapeutic agents for the …

[HTML][HTML] Silymarin attenuated hepatic steatosis through regulation of lipid metabolism and oxidative stress in a mouse model of nonalcoholic fatty liver disease (NAFLD …

X Ni, H Wang - American journal of translational research, 2016 - ncbi.nlm.nih.gov
Silymarin, which derived from the milk thistle plant (silybum marianum), has been used for
centuries as a natural remedy for diseases of the liver and biliary tract. Considering the …

[HTML][HTML] Herbal medicine in the treatment of non-alcoholic fatty liver diseases-efficacy, action mechanism, and clinical application

Y Xu, W Guo, C Zhang, F Chen, HY Tan, S Li… - Frontiers in …, 2020 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease with high
prevalence in the developed countries. NAFLD has been considered as one of the leading …

[HTML][HTML] Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development

L Wang, Y Yan, L Wu, J Peng - Pharmacological Research, 2023 - Elsevier
With changing lifestyles, non-alcoholic fatty liver disease (NAFLD) has become the most
prevalent liver disease worldwide. A substantial increase in the incidence, mortality, and …