Realizing the translational impacts of three-dimensional (3D) bioprinting for cancer research
necessitates innovation in bioprinting workflows which integrate affordability, user …

Over the past six decades the inflation-adjusted cost to bring a new drug to market has been
increasing constantly and doubles every 9 years–now reaching in excess of $2.5 billion …

Organs-on-chips (OoCs) are microfluidic devices that contain bioengineered tissues or parts
of natural tissues or organs and can mimic the crucial structures and functions of living …

The cancer microenvironment is known for its complexity, both in its content as well as its
dynamic nature, which is difficult to study using two-dimensional (2D) cell culture models …

Decades of efforts in engineering in vitro cancer models have advanced drug discovery and
the insight into cancer biology. However, the establishment of preclinical models that enable …

Organs-on-chips are in vitro models in which human tissues are cultured in microfluidic
compartments with a controlled, dynamic micro-environment. Specific organs-on-chips are …

Currently, the demand for more reliable drug screening devices has made scientists and
researchers develop novel potential approaches to offer an alternative to animal studies …

The extracellular matrix interacts with cancer cells and is a key factor in the development of
cancer. Traditional two-dimensional models cannot mimic the natural in situ environment of …

Cancerous tumors are among the most fatal diseases worldwide, claiming nearly 10 million
lives in 2020. Due to their complex and dynamic nature, modeling tumors accurately is a …

To understand the physical behavior and migration of cancer cells, a 3D in vitro micro-chip
in hydrogel was created using 3D projection printing. The micro-chip has a honeycomb …