RFC4 promotes the progression and growth of Oral Tongue squamous cell carcinoma in vivo and vitro

J Zhang, L Wang, X Xie - Journal of clinical laboratory analysis, 2021 - Wiley Online Library
Objective Currently, many studies have found that RFC4 was up‐regulated in various
cancers, and related to the progression and development. While the effects of RFC4 in oral …

RFC3 serves as a novel prognostic biomarker and target for head and neck squamous cell carcinoma

KR Avs, C Pandi, B Kannan, A Pandi… - Clinical Oral …, 2023 - Springer
Objective Head and neck squamous cell carcinoma (HNSCC) is a prevalent cancer that
originates from the squamous cells. The role of the replication factor C subunit 3 (RFC3) in …

Knockdown of RFC4 inhibits the cell proliferation of nasopharyngeal carcinoma in vitro and in vivo

S Guan, L Feng, J Wei, G Wang, L Wu - Frontiers of Medicine, 2023 - Springer
Nasopharyngeal carcinoma (NPC) is a malignant tumor that mainly occurs in East and
Southeast Asia. Although patients benefit from the main NPC treatments (eg, radiotherapy …

Identification of RFC5 as a novel potential prognostic biomarker in lung cancer through bioinformatics analysis

M Wang, T Xie, Y Wu, Q Yin, S Xie… - Oncology …, 2018 - spandidos-publications.com
Lung cancer is the leading cause of mortalities among all types of cancer. Therefore, the
screening of biomarkers that are related with the progression of lung cancer is crucial for …

Up-regulated RFC2 predicts unfavorable progression in hepatocellular carcinoma

Z Ji, J Li, J Wang - Hereditas, 2021 - Springer
Abstract Background Replication factor C (RFC) is closely related to tumor progression and
metastasis. However, the functional significance of RFC2 in hepatocellular carcinoma …

RFC2 promotes aerobic glycolysis and progression of colorectal cancer

F Lou, M Zhang - BMC gastroenterology, 2023 - Springer
Background Replication factor C subunit 2 (RFC2) participates in the growth and metastasis
of various malignancies. Our study investigated the roles of RFC2 in colorectal cancer …

[HTML][HTML] RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung …

S Gong, X Qu, S Yang, S Zhou… - International …, 2019 - spandidos-publications.com
Lung cancer is a malignant tumor responsible for the highest mortality rate in humans. The
identification of novel functional genes is of great importance in the treatment of lung cancer …

[HTML][HTML] Up-regulation of RFC3 promotes triple negative breast cancer metastasis and is associated with poor prognosis via EMT

ZY He, SG Wu, F Peng, Q Zhang, Y Luo, M Chen… - Translational …, 2017 - Elsevier
Triple-negative breast cancer (TNBC) was regarded as the most aggressive and mortal
subtype of breast cancer (BC) since the molecular subtype system has been established …

Integrative Genomics Identified RFC3 As an Amplified Candidate Oncogene in Esophageal Adenocarcinoma

WW Lockwood, KL Thu, L Lin, LA Pikor, R Chari… - Clinical Cancer …, 2012 - AACR
Purpose: Esophageal adenocarcinoma (EAC) is a lethal malignancy that can develop from
the premalignant condition, Barrett's esophagus (BE). Currently, there are no validated …

Oncogenic Potential of Replication Factor C Subunit 4: Correlations with Tumor Progression and Assessment of Potential Inhibitors

M Alaa Eldeen, F Mamdouh, WK Abdulsahib, RA Eid… - Pharmaceuticals, 2024 - mdpi.com
Replication Factor C Subunit 4 (RFC4), an oncogene implicated in many human cancers,
has yet to be extensively studied in many cancer types to determine its expression patterns …