DNA methylation analysis of full void urine and urine pellet seems promising for bladder
cancer (BC) detection and surveillance. Urinary cell-free DNA from urine supernatant is now …

Background The development of accurate urinary biomarkers for non-invasive and cost-
effective detection of primary and recurrent bladder tumours is recognized as one of the …

Background Better prognostic outcome is closely correlated with early detection of bladder
cancer. Current non-invasive urianalysis relies on simultaneously testing multiple …

Purpose: The high risk of recurrence after transurethral resection of bladder tumor of
nonmuscle invasive disease requires lifelong treatment and surveillance. Changes in DNA …

BACKGROUND Current methods for the detection and surveillance of bladder cancer (BCa)
are often invasive and/or possess suboptimal sensitivity and specificity, especially in early …

Purpose: This study aims to provide a better set of DNA methylation markers in urine
sediments for sensitive and specific detection of bladder cancer. Experimental Design: Fifty …

Changes in DNA methylation have been causally linked with cancer and provide promising
biomarkers for detection in biological fluids such as blood, urine, and saliva. The field has …

Background Aberrant DNA methylation status early in carcinogenesis represents a potential
indicator of tumor detection. We would like to establish a DNA methylation biomarker panel …

Introduction Abnormal gene methylation has been observed in several cancers. A prior
study reported methylation of TWIST1 and NID2 as a quantitative biomarker for urothelial …

Recently, there has been a great effort to develop tests based on non-invasive urinary
biomarkers (NMIBCs). These tests are based on the fact that NMIBCs are heterogeneous at …