Oxytocin (OXT) has been used to prolong the luteal phase in mares, but its mechanism of
action is unknown. The aim of this study was to evaluate the effect of chronic exogenous …

Endometrial oxytocin receptors (OXTR) and prostaglandin-endoperoxide synthase 2
(PTGS2) are central components of the luteolytic pathway in cyclic mares, and their …

The objectives were to:(1) evaluate the efficacy of varying intervals of oxytocin administration
in preventing luteolysis in mares;(2) examine PGF2α release in mares experiencing …

A procedure for oxytocin (OT) administration on Day 13 postovulation was developed in
mares for stimulation of a pulse of PGFM (a PGF2α metabolite) that mimics a natural PGFM …

The objectives of this study were to (1) compare the effect of twice versus once daily
administration of oxytocin on days 7-14 after ovulation on the duration of corpus luteum (CL) …

Recent evidence indicates that, in mares, as in the domestic ruminants, oxytocin and its
endometrial receptor play important roles in stimulating the pulsatile releases of …

Eight mature, reproductively normal, cyclic mares were included in the study. Oestrus was
induced by administration of 250 µg cloprostenol (Estrumate). Once a 35 mm follicle was …

Objective—To determine whether IM administration of exogenous oxytocin twice daily on
days 7 to 14 after ovulation blocks luteolysis and causes prolonged function of corpora lutea …

The oviduct plays important roles in the early reproductive process. The aim of this study
was to evaluate gene transcription and protein expression of progesterone receptor (PGR) …

Prolonging function of the corpus luteum (CL) is a method of suppressing estrus that relies
on continued secretion of endogenous progesterone to keep mares out of heat naturally …