Short-term effects of sevelamer-carbonate on fibroblast growth factor 23 and pulse wave velocity in patients with normophosphataemic chronic kidney disease Stage 3

A Bouma-de Krijger, FJ van Ittersum… - Clinical kidney …, 2019 - academic.oup.com
Background High concentrations of both phosphate and fibroblast growth factor 23 (FGF23)
observed in chronic kidney disease (CKD) are associated with an increased risk of …

Small steps towards the potential of 'preventive'treatment of early phosphate loading in chronic kidney disease patients

J Bover, M Cozzolino - Clinical Kidney Journal, 2019 - academic.oup.com
Few clinical studies have investigated the value of phosphate (P)-lowering therapies in early
chronic kidney disease (CKD) patients in whom hyperphosphataemia has not yet clearly …

Comparison of calcium acetate and sevelamer on vascular function and fibroblast growth factor 23 in CKD patients: a randomized clinical trial

MI Yilmaz, A Sonmez, M Saglam, H Yaman… - American journal of …, 2012 - Elsevier
BACKGROUND: Fibroblast growth factor 23 (FGF-23) is a marker of endothelial dysfunction
and atherosclerotic complications in patients with chronic kidney disease (CKD). Because …

Cardiovascular effects of sevelamer in stage 3 CKD

CD Chue, JN Townend, WE Moody… - Journal of the …, 2013 - journals.lww.com
Serum phosphate independently predicts cardiovascular mortality in the general population
and CKD, even when levels are in the normal range. Associations between serum …

Effects of phosphate binder therapy on vascular stiffness in early-stage chronic kidney disease

ME Seifert, L De Las Fuentes, M Rothstein… - American journal of …, 2013 - karger.com
Abstract Background/Aims: Cardiovascular disease (CVD) is increased in chronic kidney
disease (CKD), and contributed to by the CKD-mineral bone disorder (CKD-MBD). CKD …

Phosphate binding therapy to lower serum fibroblast-growth-factor-23 concentrations in chronic kidney disease: rationale and study design of the Sevelamer on …

AY Adema, MA de Jong, MH de Borst, PM Ter Wee… - Nephron, 2016 - karger.com
Background: Increased levels of phosphate and fibroblast growth factor-23 (FGF23) are
strong predictors of cardiovascular morbidity and mortality in patients with chronic kidney …

Effect of a non-calcium-based phosphate binder on fibroblast growth factor 23 in chronic kidney disease

C Spatz, K Roe, E Lehman, N Verma - Nephron Clinical Practice, 2013 - karger.com
Background: Elevated fibroblast growth factor 23 (FGF23) levels are associated with
progression of chronic kidney disease (CKD) and increased mortality. Studies in individuals …

[HTML][HTML] Effects of sevelamer treatment on cardiovascular abnormalities in mice with chronic renal failure

J Maizel, I Six, S Dupont, E Secq, B Dehedin… - Kidney international, 2013 - Elsevier
Elevated serum phosphate and fibroblast growth factor 23 (FGF23) levels are associated
with cardiovascular disease (CVD) in patients with chronic renal failure (CRF). The …

Long‐term sevelamer treatment lowers serum fibroblast growth factor 23 accompanied with increasing serum K lotho levels in chronic haemodialysis patients

HH Lin, HH Liou, MS Wu, CY Lin, CC Huang - Nephrology, 2014 - Wiley Online Library
Aims Fibroblast growth factor 23 (FGF 23) and K lotho are associated with vascular
calcification and cardiovascular disease in dialysis patients. Sevelamer has been shown to …

Randomized clinical trial of sevelamer carbonate on serum klotho and fibroblast growth factor 23 in CKD

S Liabeuf, JP Ryckelynck, N El Esper… - Clinical Journal of the …, 2017 - journals.lww.com
Results Of 96 screened patients, 78 (mean±SD age: 63±13 years old; 70% men; mean
eGFR: 27±9 ml/min per 1.73 m 2) met the inclusion criteria. At baseline, mean eGFR was …