Continued search for therapies to favorably modify phosphate and FGF23 levels in CKD

R Mehta, T Isakova - Clinical Journal of the American Society of …, 2017 - journals.lww.com
Over the last two decades, scientific developments have enhanced our understanding of the
pathogenesis of cardiovascular disease in patients with CKD, and specific nontraditional risk …

Systematic review and meta‐analysis of potential pleiotropic effects of sevelamer in chronic kidney disease: Beyond phosphate control

RS Basutkar, R Varghese, NK Mathew… - …, 2022 - Wiley Online Library
Sevelamer, has been shown to have many pleiotropic actions on lipid panel, various
inflammatory markers, and blood glucose levels in chronic kidney disease patients. We …

[HTML][HTML] Significance of acPWV for survival of hemodialysis patients

M Petrovic, M Baralic, V Brkovic, A Arsenovic… - Medicina, 2020 - mdpi.com
Background and Objectives: Abnormal arterial stiffness (AS) is a major complication in end-
stage kidney disease (ESKD) patients treated by dialysis. Our study aimed to determine the …

[HTML][HTML] FGF23, PTH and phosphorus metabolism in the chronic renal insufficiency cohort

T Isakova, P Wahl, G Vargas, OM Gutiérrez… - Kidney …, 2011 - ncbi.nlm.nih.gov
Abstract Fibroblast growth factor 23 (FGF23) regulates phosphorus metabolism and is a
strong predictor of mortality in dialysis patients. FGF23 has been proposed as an early …

Levels of FGF23 predict outcomes in advanced CKD

C Greenhill - Nature Reviews Nephrology, 2011 - nature.com
The researchers found that raised plasma levels of FGF23 were strongly associated with all-
cause mortality, cardiovascular events and progression to chronic dialysis. This association …

Fibroblast growth factor-23 levels are associated with vascular calcifications in peritoneal dialysis patients

E Asicioglu, A Kahveci, H Arikan, M Koc… - Nephron Clinical …, 2013 - karger.com
Background: The aim of the study was to assess the relationship between fibroblast growth
factor-23 (FGF-23) and vascular calcifications (VC) in peritoneal dialysis (PD) patients …

High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients

G Jean, JC Terrat, T Vanel, JM Hurot… - Nephrology Dialysis …, 2009 - academic.oup.com
Background. Fibroblast growth factor (FGF)-23, a novel bone-derived phosphaturic factor
involved in mineral metabolism, is increased in chronic kidney disease (CKD); in dialysis …

FGF-23: the rise of a novel cardiovascular risk marker in CKD

GH Heine, S Seiler, D Fliser - Nephrology Dialysis …, 2012 - academic.oup.com
Elevated plasma levels of the phosphaturic hormone fibroblast growth factor 23 (FGF-23)
are a hallmark of chronic kidney disease (CKD)-mineral and bone disorder. FGF-23 allows …

Acetate-free biofiltration to remove fibroblast growth factor 23 in hemodialysis patients: a pilot study

V Cernaro, S Lucisano, V Canale, A Bruzzese… - Journal of …, 2018 - Springer
Aim Serum levels of 32 kDa-phosphaturic hormone fibroblast growth factor 23 (FGF23) rise
early in renal failure in order to keep phosphatemia within the normal range; however, this …

[HTML][HTML] Nephron index rather than serum FGF 23 predicts endothelial dysfunction in early but not advanced chronic kidney disease patients

N Khreba, D Khedr, A Abdel-Baky, GE Kannishy… - … Urology and Nephrology, 2023 - Springer
Background Endothelial dysfunction is the primary step for the development of CKD-related
cardiovascular disease. Early prediction and management can influence patient survival …