[HTML][HTML] Gastric cancer: advances in carcinogenesis research and new therapeutic strategies

L Seeneevassen, E Bessède, F Mégraud… - International journal of …, 2021 - mdpi.com
Gastric cancer's bad incidence, prognosis, cellular and molecular heterogeneity amongst
others make this disease a major health issue worldwide. Understanding this affliction is a …

Gastric cancer: Basic aspects

S Molina‐Castro, J Pereira‐Marques… - …, 2017 - Wiley Online Library
Gastric cancer is one of the most incident and deadliest malignancies in the world. Gastric
cancer is a heterogeneous disease and the end point of a long and multistep process, which …

[HTML][HTML] Gastric cancer review

LP Carcas - Journal of carcinogenesis, 2014 - ncbi.nlm.nih.gov
Gastric cancer is an aggressive disease that continues to have a daunting impact on global
health. Despite an overall decline in incidence over the last several decades, gastric cancer …

Gastric cancer: a comprehensive review of current and future treatment strategies

RE Sexton, MN Al Hallak, M Diab, AS Azmi - Cancer and Metastasis …, 2020 - Springer
Gastric cancer remains a major unmet clinical problem with over 1 million new cases
worldwide. It is the fourth most commonly occurring cancer in men and the seventh most …

[HTML][HTML] Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy

I Riquelme, K Saavedra, JA Espinoza, H Weber… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the third leading cause of cancer mortality worldwide. Although
surgical resection is a potentially curative approach for localized cases of GC, most cases of …

[HTML][HTML] New advances in targeted gastric cancer treatment

DC Lazăr, S Tăban, M Cornianu, A Faur… - World journal of …, 2016 - ncbi.nlm.nih.gov
Despite a decrease in incidence over past decades, gastric cancer remains a major global
health problem. In the more recent period, survival has shown only minor improvement …

The role of the gastric bacterial microbiome in gastric cancer: Helicobacter pylori and beyond

C Schulz, K Schütte, J Mayerle… - Therapeutic …, 2019 - journals.sagepub.com
A link between chronic inflammation and carcinogenesis has been depicted in many organ
systems. Helicobacter pylori is the most prevalent bacterial pathogen, induces chronic …

Gastric cancer—molecular and clinical dimensions

R Wadhwa, S Song, JS Lee, Y Yao, Q Wei… - Nature reviews Clinical …, 2013 - nature.com
Gastric cancer imposes a considerable health burden around the globe despite its declining
incidence. The disease is often diagnosed in advanced stages and is associated with a poor …

Stem cells, helicobacter pylori, and mutational landscape: utility of preclinical models to understand carcinogenesis and to direct management of gastric cancer

D Liabeuf, M Oshima, DE Stange, M Sigal - Gastroenterology, 2022 - Elsevier
Several genetic and environmental factors increase gastric cancer (GC) risk, with
Helicobacter pylori being the main environmental agent. GC is thought to emerge through a …

Helicobacter pylori Infection, Oncogenic Pathways and Epigenetic Mechanisms in Gastric Carcinogenesis

SZ Ding, JB Goldberg, M Hatakeyama - Future oncology, 2010 - Taylor & Francis
Chronic colonization of the human stomach by Helicobacter pylori, a Gram-negative
bacterium, is the major cause of chronic gastritis, peptic ulcers and gastric cancer. Recent …