Targeting oxidative stress and endothelial dysfunction using tanshinone IIA for the treatment of tissue inflammation and fibrosis

TC Lu, YH Wu, WY Chen… - Oxidative Medicine and …, 2022 - Wiley Online Library
Salvia miltiorrhiza Burge (Danshen), a member of the Lamiaceae family, has been used in
traditional Chinese medicine for many centuries as a valuable medicinal herb with …

Pharmacological activity and mechanism of tanshinone IIA in related diseases

R Guo, L Li, J Su, S Li, SE Duncan, Z Liu… - Drug Design …, 2020 - Taylor & Francis
Salvia miltiorrhiza:(Danshen) is a significant (traditional Chinese medication) natural
remedy, enhancing blood circulation and clear blood stasis. In this view, it is widely used …

[Retracted] A Pharmacological Review of Tanshinones, Naturally Occurring Monomers from Salvia miltiorrhiza for the Treatment of Cardiovascular Diseases

Y Yang, M Shao, W Cheng, J Yao, L Ma… - Oxidative Medicine …, 2023 - Wiley Online Library
Cardiovascular diseases (CVDs) are a set of heart and blood vessel disorders that include
coronary heart disease (CHD), rheumatic heart disease, and other conditions. Traditional …

Cardiovascular actions and therapeutic potential of tanshinone IIA

S Gao, Z Liu, H Li, PJ Little, P Liu, S Xu - Atherosclerosis, 2012 - Elsevier
Tanshinone IIA (TS), a pharmacologically active component isolated from the rhizome of the
Chinese herb Salvia miltiorrhiza Bunge (Danshen), has been clinically used in Asian …

Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways

C Pan, L Lou, Y Huo, G Singh, M Chen… - Therapeutic …, 2011 - journals.sagepub.com
Objective: Salvia miltiorrhiza (Danshen) has been widely used for the treatment of cardiac
and cerebrovascular disease throughout history. The objective of this study is to further …

Oxidative Stress and Salvia miltiorrhiza in Aging‐Associated Cardiovascular Diseases

CC Chang, YC Chang, WL Hu… - Oxidative Medicine and …, 2016 - Wiley Online Library
Aging‐associated cardiovascular diseases (CVDs) have some risk factors that are closely
related to oxidative stress. Salvia miltiorrhiza (SM) has been used commonly to treat CVDs …

The effect of salvianolic acid on vascular protection and possible mechanisms

Y Wu, S Xu, XY Tian - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
Salvia miltiorrhiza (Danshen), as an important traditional Chinese medicinal plant, has been
used in China for the treatment of cardiovascular diseases for hundreds of years. Salvianolic …

Molecular Signaling Pathways Behind the Biological Effects of Salvia Species Diterpenes in Neuropharmacology and Cardiology

M Akaberi, M Iranshahi, S Mehri - Phytotherapy Research, 2016 - Wiley Online Library
The genus Salvia, from the Lamiaceae family, has diverse biological properties that are
primarily attributable to their diterpene contents. There is no comprehensive review on the …

Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection

JHC Ho, CY Hong - Journal of biomedical science, 2011 - Springer
Salvianolic acids are the most abundant water-soluble compounds extracted from Radix
Salvia miltiorrhiza (Danshen). In China, Danshen has been wildly used to treat …

[HTML][HTML] Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2

X Ma, L Zhang, F Gao, W Jia, C Li - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The mechanisms of Salvia miltiorrhiza (SM) and Tanshinone IIA (Tan IIA) in the treatment of
atherosclerosis was examined by combining network pharmacology and molecular biology …