Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling

L Wang, L Hu, X Zhou, Z Xiong, C Zhang… - Scientific Reports, 2017 - nature.com
Scar formation is an intractable medical problem that appears after skin wounds have
healed. Recent research has shown that exosomes secreted by human adipose …

Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

Adipose mesenchymal stem cell-derived exosomes promote wound healing through the WNT/β-catenin signaling pathway in dermal fibroblasts

C Li, Y An, Y Sun, F Yang, Q Xu, Z Wang - Stem Cell Reviews and Reports, 2022 - Springer
The differentiation, migration, and proliferation of skin fibroblasts are identified as key factors
in cutaneous wound healing. Adipose-derived mesenchymal stem cells (ADMSCs) and their …

Human exosomes accelerate cutaneous wound healing by promoting collagen synthesis in a diabetic mouse model

B Zhao, X Zhang, Y Zhang, Y Lu, W Zhang… - Stem Cells and …, 2021 - liebertpub.com
Chronic wounds including diabetic foot ulcers are clinical emergencies that need careful
management. Exosomes from human adipose-derived mesenchymal stem cells (hADSCs …

Epidermal stem cell-derived exosomes promote skin regeneration by downregulating transforming growth factor-β1 in wound healing

M Duan, Y Zhang, H Zhang, Y Meng, M Qian… - Stem cell research & …, 2020 - Springer
Background Scar formation, which may be caused by myofibroblast aggregations, is the
greatest challenge during skin wound healing in the clinical setting. Studies have indicated …

Combined topical and systemic administration with human adipose-derived mesenchymal stem cells (hADSC) and hADSC-derived exosomes markedly promoted …

Y Zhou, B Zhao, XL Zhang, Y Lu, ST Lu… - Stem cell research & …, 2021 - Springer
Background Cutaneous wound healing and regeneration have become a recognized health
challenge in the world, which causes severe damage to the mental and physical health of …

Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway

W Zhang, X Bai, B Zhao, Y Li, Y Zhang, Z Li… - Experimental cell …, 2018 - Elsevier
Introduction Adipose tissue-derived stem cells (ADSCs) have been shown to enhance
wound healing via their paracrine function. Exosomes, as one of the most important …

Adipose mesenchymal stem cell exosomes promote wound healing through accelerated keratinocyte migration and proliferation by activating the AKT/HIF-1α axis

Y Zhang, F Han, L Gu, P Ji, X Yang, M Liu… - Journal of Molecular …, 2020 - Springer
Accelerating wound healing is a key consideration for surgeons. The three stages of wound
healing include the inflammatory response, cell proliferation and tissue repair, and much …

Human adipose mesenchymal stem cell-derived exosomes: a key player in wound healing

JS Heo, S Kim, CE Yang, Y Choi, SY Song… - Tissue Engineering and …, 2021 - Springer
Background: Human adipose-derived mesenchymal stem cells (AMSCs) are an attractive
resource for wound healing because their regenerative capacity improves injury repair …

Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration

Y Zhou, XL Zhang, ST Lu, NY Zhang, HJ Zhang… - Stem cell research & …, 2022 - Springer
Background Large area skin trauma has always been a great challenge for both patients
and clinicians. Exosomes originating from human adipose-derived mesenchymal stem cells …