Mesenchymal stem cell exosomes induce proliferation and migration of normal and chronic wound fibroblasts, and enhance angiogenesis in vitro

A Shabbir, A Cox, L Rodriguez-Menocal… - Stem cells and …, 2015 - liebertpub.com
Although chronic wounds are common and continue to be a major cause of morbidity and
mortality, treatments for these conditions are lacking and often ineffective. A large body of …

Exosomes secreted from induced pluripotent stem cell-derived mesenchymal stem cells accelerate skin cell proliferation

S Kim, SK Lee, H Kim, TM Kim - International journal of molecular …, 2018 - mdpi.com
Induced pluripotent stem cell (iPSC)-derived mesenchymal stem cells (iMSCs) serve as a
unique source for cell therapy. We investigated whether exosomes from iMSCs promote the …

Application of ADSCs and their exosomes in scar prevention

C Li, S Wei, Q Xu, Y Sun, X Ning, Z Wang - Stem Cell Reviews and …, 2022 - Springer
Scar is a common way of healing after tissue injury. The poor scar healing will not only
cause dysfunction of tissues and organs but also affect the appearance of the patients' body …

The functions and clinical application potential of exosomes derived from mesenchymal stem cells on wound repair: a review of recent research advances

X Qin, J He, X Wang, J Wang, R Yang… - Frontiers in …, 2023 - frontiersin.org
Wound repair is a complex problem for both clinical practitioners and scientific investigators.
Conventional approaches to wound repair have been associated with several limitations …

Mesenchymal stromal cells-exosomes: a promising cell-free therapeutic tool for wound healing and cutaneous regeneration

P Hu, Q Yang, Q Wang, C Shi, D Wang… - Burns & …, 2019 - academic.oup.com
Cutaneous regeneration at the wound site involves several intricate and dynamic processes
which require a series of coordinated interactions implicating various cell types, growth …

Exosomes derived from human amniotic epithelial cells accelerate wound healing and inhibit scar formation

B Zhao, Y Zhang, S Han, W Zhang, Q Zhou… - Journal of molecular …, 2017 - Springer
Wound healing is a highly orchestrated physiological process consisting of a complex
events, and scarless wound healing is highly desired for the development and application in …

Human adipose-derived mesenchymal stem cells-derived exosomal microRNA-19b promotes the healing of skin wounds through modulation of the CCL1/TGF-β …

G Cao, B Chen, X Zhang, H Chen - Clinical, Cosmetic and …, 2020 - Taylor & Francis
Introduction Human adipose-derived mesenchymal stem cells (ADMSCs) with their
secretory factors are able to induce collagen synthesis and fibroblast migration in the wound …

Extracellular vesicles from adipose‐derived mesenchymal stem/stromal cells accelerate migration and activate AKT pathway in human keratinocytes and fibroblasts …

AF Ferreira, PS Cunha, VM Carregal… - Stem Cells …, 2017 - Wiley Online Library
Mesenchymal stem/stromal cells (MSCs) are promising tools in cell therapy. They secrete
extracellular vesicles (EVs) that carry different classes of molecules that can promote skin …

Exosomes derived from autologous dermal fibroblasts promote diabetic cutaneous wound healing through the Akt/β-catenin pathway

X Han, P Wu, L Li, HM Sahal, C Ji, J Zhang, Y Wang… - Cell Cycle, 2021 - Taylor & Francis
Diabetic cutaneous wounds are one of the complications of diabetes mellitus (DM) and are
difficult to cure at present. Autologous dermal fibroblasts (DFs) have shown great promise in …

Fetal dermal mesenchymal stem cell‐derived exosomes accelerate cutaneous wound healing by activating notch signaling

X Wang, Y Jiao, Y Pan, L Zhang, H Gong… - Stem Cells …, 2019 - Wiley Online Library
Fetal dermal mesenchymal stem cells (FDMSCs), isolated from fetal skin, are serving as a
novel MSC candidate with great potential in regenerative medicine. More recently, the …