Differential wound healing capacity of mesenchymal stem cell-derived exosomes originated from bone marrow, adipose tissue and umbilical cord under serum-and …

DH Hoang, TD Nguyen, HP Nguyen… - Frontiers in molecular …, 2020 - frontiersin.org
Exosomes are nano-scale and closed membrane vesicles which are promising for
therapeutic applications due to exosome-enclosed therapeutic molecules such as DNA …

Stem cell-derived exosomes for wound healing: current status and promising directions.

NB Vu, HT Nguyen, R Palumbo, R Pellicano… - Minerva …, 2020 - europepmc.org
Wound healing, especially of chronic wounds, is still an unmet therapeutic area since
assessment and management are extremely complicated. Although many efforts have been …

HucMSC-exosome mediated-Wnt4 signaling is required for cutaneous wound healing

B Zhang, M Wang, A Gong, X Zhang, X Wu, Y Zhu… - Stem …, 2015 - academic.oup.com
Mesenchymal stem cell-derived exosomes (MSC-Ex) play important roles in tissue injury
repair, however, the roles of MSC-Ex in skin damage repair and its mechanisms are largely …

Extracellular vesicle‐enclosed miR‐486‐5p mediates wound healing with adipose‐derived stem cells by promoting angiogenesis

Y Lu, H Wen, J Huang, P Liao, H Liao… - Journal of Cellular …, 2020 - Wiley Online Library
Adipose‐derived stem cells (ASC) are said to have a pivotal role in wound healing.
Specifically, ASC‐secreted extracellular vesicles (EV) carry diverse cargos such as …

Exosomes are comparable to source adipose stem cells in fat graft retention with up-regulating early inflammation and angiogenesis

B Chen, J Cai, Y Wei, Z Jiang… - Plastic and …, 2019 - journals.lww.com
Background: Exosomes derived from mesenchymal stem cells possess functional properties
similar to those of their parent cells, suggesting that they could play a pivotal role in tissue …

Exosomes from human adipose tissue-derived mesenchymal stem cells promote epidermal barrier repair by inducing de novo synthesis of ceramides in atopic …

KO Shin, DH Ha, JO Kim, DA Crumrine, JM Meyer… - Cells, 2020 - mdpi.com
Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal
barrier disruption and intense systemic inflammation. Previously, we showed that exosomes …

Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway

M Yu, W Liu, J Li, J Lu, H Lu, W Jia, F Liu - Stem cell research & therapy, 2020 - Springer
Background Mesenchymal stem cell (MSC)-derived exosomes emerge as promising
candidates for treating delayed wound healing in diabetes due to the promotion of …

Exosomes derived from mmu_circ_0000250-modified adipose-derived mesenchymal stem cells promote wound healing in diabetic mice by inducing miR-128-3p …

R Shi, Y Jin, W Hu, W Lian, C Cao… - … of Physiology-Cell …, 2020 - journals.physiology.org
More and more evidence advises that circular RNAs (circRNAs) function critically in
regulating different disease microenvironments. Our previous study found that …

MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy

F Marofi, KI Alexandrovna, R Margiana… - Stem Cell Research & …, 2021 - Springer
Currently, mesenchymal stem/stromal stem cell (MSC) therapy has become a promising
option for accelerating cutaneous wound healing. In vivo reports have outlined the robust …

[HTML][HTML] Exosome derived from mesenchymal stem cells alleviates pathological scars by inhibiting the proliferation, migration and protein expression of fibroblasts via …

W Zhao, R Zhang, C Zang, L Zhang… - International Journal …, 2022 - ncbi.nlm.nih.gov
Methods MSC-Exo was isolated and identified by ultracentrifugation, transmission electron
microscopy, nanoparticle size measuring instrument and Western blot assays. The …