[HTML][HTML] Enhanced Codelivery of Gefitinib and Azacitidine for Treatment of Metastatic-Resistant Lung Cancer Using Biodegradable Lipid Nanoparticles
Lung cancer is a formidable challenge in clinical practice owing to its metastatic nature and
resistance to conventional treatments. The codelivery of anticancer agents offers a potential …
resistance to conventional treatments. The codelivery of anticancer agents offers a potential …
Co-encapsulated nanoparticles of Erlotinib and Quercetin for targeting lung cancer through nuclear EGFR and PI3K/AKT inhibition
Erlotinib-based EGFR targeted therapy has proven significant clinical improvement against
non-small cell lung cancer (NSCLC). However, the anticancer activity of Erlotinib (Ertb) is …
non-small cell lung cancer (NSCLC). However, the anticancer activity of Erlotinib (Ertb) is …
Polymer–lipid hybrid nanoparticles conjugated with anti-EGF receptor antibody for targeted drug delivery to hepatocellular carcinoma
J Gao, Y Xia, H Chen, Y Yu, J Song, W Li, W Qian… - …, 2014 - Taylor & Francis
Aims: The aim of this study was to obtain adriamycin-loaded polymer–lipid hybrid
nanoparticles conjugated with anti-EGF receptor antibody (PLNP-Mal-EGFR) for …
nanoparticles conjugated with anti-EGF receptor antibody (PLNP-Mal-EGFR) for …
Injectable thermosensitive hydrogel containing erlotinib‐loaded hollow mesoporous silica nanoparticles as a localized drug delivery system for NSCLC therapy
X Zhou, X He, K Shi, L Yuan, Y Yang, Q Liu… - Advanced …, 2020 - Wiley Online Library
Erlotinib (ERT), oral administration agents, is one of the most pivotal targeted drugs in the
treatment of non‐small cell lung cancer (NSCLC); however, its poor solubility, low oral …
treatment of non‐small cell lung cancer (NSCLC); however, its poor solubility, low oral …
Aptamer-conjugated chitosan-anchored liposomal complexes for targeted delivery of erlotinib to EGFR-mutated lung cancer cells
F Li, H Mei, X Xie, H Zhang, J Liu, T Lv, H Nie, Y Gao… - The AAPS journal, 2017 - Springer
Lung cancer is the leading cancer and has the highest death rate. The epidermal growth
factor receptor (EGFR) tyrosine kinase inhibitor (TKI) erlotinib has had a promising response …
factor receptor (EGFR) tyrosine kinase inhibitor (TKI) erlotinib has had a promising response …
Combination chemotherapy of lung cancer–co-delivery of docetaxel prodrug and cisplatin using aptamer-decorated lipid–polymer hybrid nanoparticles
R Wu, Z Zhang, B Wang, G Chen, Y Zhang… - Drug design …, 2020 - Taylor & Francis
Purpose Lung cancer is the leading cause of cancer mortality worldwide. Drug resistance is
the major barrier for the treatment of non-small cell lung cancer (NSCLC). The aim of this …
the major barrier for the treatment of non-small cell lung cancer (NSCLC). The aim of this …
Co-Delivery of erlotinib and resveratrol via nanostructured lipid Carriers: a synergistically promising approach for cell proliferation prevention and ROS-Mediated …
L Asadollahi, A Mahoutforoush, SS Dorreyatim… - International journal of …, 2022 - Elsevier
Cancer treatments are always associated with various challenges, and scientists are
constantly trying to find new therapies and methods. Erlotinib (ELT) is a well-known …
constantly trying to find new therapies and methods. Erlotinib (ELT) is a well-known …
Biomacromolecule/lipid hybrid nanoparticles for controlled delivery of sorafenib in targeting hepatocellular carcinoma therapy
J Zhang, T Wang, S Mu, LD Olerile, X Yu, N Zhang - Nanomedicine, 2017 - Taylor & Francis
Aim: Hybrids composed of various materials are highly versatile for drug delivery in tumor
therapy including hepatocellular carcinoma. Herein, a sorafenib (SF)-loaded …
therapy including hepatocellular carcinoma. Herein, a sorafenib (SF)-loaded …
[HTML][HTML] Comparative of in-vitro evaluation between erlotinib loaded nanostructured lipid carriers and liposomes against A549 lung cancer cell line
FA Gaballu, S Abbaspour-Ravasjani… - Iranian journal of …, 2019 - ncbi.nlm.nih.gov
Erlotinib (ELT) as a small molecule with poor solubility, poor bioavailability, and instability in
gastrointestinal environment, has been considered as a therapeutic agent for Non-Small …
gastrointestinal environment, has been considered as a therapeutic agent for Non-Small …
Cyclodextrin modified erlotinib loaded PLGA nanoparticles for improved therapeutic efficacy against non-small cell lung cancer
This study was aimed at developing a nanoparticle strategy to overcome acquired
resistance against erlotinib in non-small cell lung cancer (NSCLC). To load erlotinib on …
resistance against erlotinib in non-small cell lung cancer (NSCLC). To load erlotinib on …