The progression of lung cancer is highly associated with the aberrant activation of epidermal
growth factor receptor (EGFR) tyrosine kinase and the positive feedback loop between …

At present, cancer is the most deadly disease and one of the most common causes of death
worldwide providing different obstacles to chemotherapy including non-specific …

Targeted delivery of natural bioactive molecules has the potential to reduce toxicity while
increasing anticancer therapeutic efficacy. Nanoparticles (NPs) conjugated with targeting …

Lung cancer remains the leading cause of cancer associated deaths worldwide. Recent
efforts have been focused on combinational and nanoparticulate therapies that can …

The aim of the present study is to design a novel dual-ligand lipid based nanoparticle
system. It is conducted by a specific ligand and pH sensitive lipid conjugate. Docetaxel …

Since the anticancer drugs exhibited a variety of inhibitory mechanisms in cancer cells, the
use of two or more anticancer drugs may have excellent therapeutic effects, particularly in …

Most anticancer drugs often fail in clinical trials due to poor solubility, poor bioavailability,
lack of targeted delivery and several off-target effects. Polymeric nanoparticles such as poly …

The current study was aimed to prepare a molecular complex of erlotinib (ERL) with
phospholipid (PC) for enhancement of solubility and thus bioavailability, therapeutic efficacy …

For treatment of colorectal cancer and to improve intravascular bioavailability, Encorafenib
(ECF) encapsulated Hyaluronic Acid (HA) decorated polycaprolactone (PCL), and …

The therapeutic efficacy of anti-cancer nanomedicines is generally constrained due to
limited accumulation in the solid tumors. In this study, we developed a biomimetic nano …