Inhaled chemotherapy for the treatment of lung tumors requires that drug delivery systems
improve selectivity for cancer cells and tumor penetration and allow sufficient lung …

In this study, the novel carrier materials were screened to structure targeting nano-micelles
(named 'nano-dandelion') for synchronous delivery of curcumin (Cur) and baicalin (Bai) …

Purpose Hepatocellular carcinoma (HCC) is a leading cancer worldwide. In the present
investigation, sorafenib (SFN) and curcumin (CCM) were co-delivered using pH-sensitive …

Solid lipid nanoparticles (SLNs) are suitable candidates for the delivery of various anti-
cancer drugs. However, currently insufficient tumor-permeability and non-specific uptake by …

This work investigated the preparation of specific targeted drug delivery systems in cancer
chemotherapy by folate conjugated human serum albumin nanoparticles encapsulated …

Non-small-cell lung cancer (NSCLC) accounts for over 85% of clinical lung cancer cases,
which is the leading cause of cancer-related death. To develop new therapeutic strategy for …

Anticancer drug‐loaded nanoparticles have been explored extensively to decrease side
effects while improving their therapeutic efficacy. However, due to the low drug loading …

Molecularly targeted drug delivery systems represent a novel therapeutic strategy in the
treatment of different cancers. In the present study, we have developed gemcitabine (GEM) …

Background Inhalation of chemotherapeutic drugs directly into the lungs augments the drug
exposure to lung cancers. The inhalation of free drugs however results in over exposure and …

Recent studies of signaling networks point out that an order of drugs to be administrated to
the cancerous cells can be critical for optimal therapeutic outcomes of recalcitrant metastatic …