Scandenolone from Cudrania tricuspidata fruit extract suppresses the viability of breast cancer cells (MCF-7) in vitro and in vivo

X Jiang, C Cao, W Sun, Z Chen, X Li, L Nahar… - Food and chemical …, 2019 - Elsevier
Scandenolone, an isoflavone, has shown anti-cancer potential. In this study, we extracted
scandenolone from Cudrania tricuspidata fruit and evaluated its anti-breast cancer effects as …

Scandenolone, a natural isoflavone derivative from Cudrania tricuspidata fruit, targets EGFR to induce apoptosis and block autophagy flux in human melanoma cells

Y Hu, Z Li, L Wang, L Deng, J Sun, X Jiang… - Journal of functional …, 2017 - Elsevier
Natural isoflavones have been reported to have a potential of antineoplastic activity.
However, novel and specific isoflavones are still needed to be explored, and the underlying …

Cudraticusxanthone A isolated from the roots of Cudrania tricuspidata inhibits metastasis and induces apoptosis in breast cancer cells

SM Jeon, DS Lee, GS Jeong - Journal of ethnopharmacology, 2016 - Elsevier
Ethnopharmacological relevance The roots of Cudrania tricuspidata is a deciduous tree
found in Korea, China, and Japan. C. tricuspidata contains an abundance of various …

5, 7, 4⿲-Trihydroxy-6, 8-diprenylisoflavone and lupalbigenin, active components of Derris scandens, induce cell death on breast cancer cell lines

A Tedasen, S Sukrong, B Sritularak, T Srisawat… - Biomedicine & …, 2016 - Elsevier
Background Natural products are a potential source for cancer chemotherapeutic
development. This current study was performed to investigate the anti-tumor potential of 5, 7 …

Phytochemical Composition, Bioavailability and Pharmacokinetics of Scorzonera undulata Methanolic Extracts: Antioxidant, Anticancer, and Apoptotic Effects on …

I Bédoui, HB Nasr, K Ksouda, W Ayadi… - Pharmacognosy …, 2024 - journals.sagepub.com
Background Finding new effective substances to develop drugs against cancer or to prevent
it remains a big challenge facing scientists and clinicians. Objectives In such an issue, we …

[HTML][HTML] The cytotoxicity and apoptotic effects of verbascoside on breast cancer 4T1 cell line

A Daneshforouz, S Nazemi, O Gholami… - BMC Pharmacology and …, 2021 - Springer
Background Despite significant advancements in breast cancer therapy, novel drugs with
lower side effects are still being demanded. In this regard, we investigated the anti-cancer …

[HTML][HTML] Synergistic anticancer effects of a bioactive subfraction of Strobilanthes crispus and tamoxifen on MCF-7 and MDA-MB-231 human breast cancer cell lines

NS Yaacob, NNNM Kamal, MN Norazmi - BMC complementary and …, 2014 - Springer
Background Development of tumour resistance to chemotherapeutic drugs and concerns
over their toxic effects has led to the increased use of medicinal herbs or natural products by …

[HTML][HTML] Apoptosis cell death effect of scrophularia variegata on breast cancer cells via mitochondrial intrinsic pathway

A Azadmehr, R Hajiaghaee, B Baradaran… - Advanced …, 2015 - ncbi.nlm.nih.gov
Purpose: Scrophularia variegata M. Beib.(Scrophulariaceae) is an Iranian medicinal plant
which is used for various inflammatory disorders in traditional medicine. In this study we …

[HTML][HTML] Cryptotanshinone induces ROS-mediated apoptosis in human gastric cancer cells

C Liu, HN Sun, YH Luo, XJ Piao, DD Wu, LQ Meng… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Cryptotanshinone (CT), isolated from the plant Salvia miltiorrhiza Bunge, has been reported
to have potential anticancer effects on human prostate and breast cancer cells. However, the …

Cytotoxic and apoptotic activity of Scrophularia oxysepala in MCF-7 human breast cancer cells

S Valiyari, R Jahanban-Esfahlan… - Toxicological & …, 2013 - Taylor & Francis
Breast cancer is the most common cancer in women. Therefore, there is an urgent need to
identify and develop therapeutic strategies against this deadly disease. This study is the first …