Transient Daratumumab-Induced Refractive Shift in Multidrug-Resistant Multiple Myeloma: Case Report and Literature Review

S Troisi, V Giudice, M Troisi, D Morini, A Crudele… - Acta …, 2023 - karger.com
Daratumumab, an anti-CD38 monoclonal antibody, is worldwide approved for treatment of
newly diagnosed and relapsed/refractory multiple myeloma (MM) patients and is available …

Bilateral secondary angle closure during daratumumab infusion: a case report and review of the literature

RG Edwards, S Vanderhoof, A Palestine… - Journal of …, 2020 - journals.lww.com
Daratumumab is an anti-CD38 monoclonal antibody approved for use in multiple myeloma
in 2015 and under investigation for use in light-chain amyloidosis. We report a case of a …

Daratumumab‐induced transient myopic shift and its proposed mechanisms.

DZ Chen, MCD Aquino, WJ Chng… - Clinical & …, 2021 - search.ebscohost.com
Daratumumab (Darzalex) is a human CD38-directed monoclonal antibody that is approved
for the treatment of refractory multiple myeloma (MM). 1 In this article, we report a case of …

Choroidal effusion: a rare and unusual complication of daratumumab

A Singh, T Bazzi, D Lebovic… - BMJ Case Reports CP, 2022 - casereports.bmj.com
Daratumumab-containing regimens are an effective treatment for advanced cases of
multiple myeloma. Overall, daratumumab has a favourable safety profile, although rare side …

Overcome daratumumab's severe life-threatening reaction by desensitization in relapsed multiple myeloma: A case report.

T NL, Y HG, M VT, D NV - Journal of Oncology Pharmacy …, 2023 - search.ebscohost.com
Introduction: Multiple myeloma has evolved markedly but the mortality remains high.
Daratumumab, a monoclonal antibody directly against CD38 antigen on the myeloma cells …

Practical considerations and role of Daratumumab retreatment for relapsed refractory Multiple Myeloma

EB Kim, C Harrington, A Yee… - Clinical …, 2019 - clinical-lymphoma-myeloma …
Background Daratumumab is a first-in-class anti-CD38 monoclonal antibody approved for
multiple myeloma. Because of the incidence and severity of infusion-related reactions with …

Daratumumab efficacy in extramedullary orbital myeloma

A Gozzetti, A Cerase, M Bocchia - Clinical Case Reports, 2020 - Wiley Online Library
Daratumumab is very efficacious in multiple myeloma. Few reports are present about
efficacy in extramedullary myeloma. We report here daratumumab efficacy in extramedullary …

[HTML][HTML] Deep sustained response to daratumumab monotherapy associated with T-cell expansion in triple refractory myeloma

SZ Usmani, I Khan, C Chiu, D Foureau… - … hematology & oncology, 2018 - Springer
Background Daratumumab, a human CD38 monoclonal antibody that has direct on-tumor
and immunomodulatory mechanisms of action, demonstrated clinical benefit as …

[PDF][PDF] Successful Desensitization to Daratumumab After a Severe Life-threatening Reaction in a Patient With Refractory Multiple Myeloma

I Cajal - J Investig Allergol Clin Immunol, 2021 - jiaci.org
Multiple myeloma (MM) is a clonal proliferation of malignant bone marrow plasma cells with
high and uniform expression of CD38 [1]. Survival has improved with autologous stem cell …

[HTML][HTML] Management of infusion-related reactions following daratumumab monotherapy in patients with at least 3 lines of prior therapy or double refractory multiple …

PM Voorhees, B Weiss, S Usmani, H Feng, C Uhlar… - Blood, 2015 - Elsevier
Abstract Introduction: Daratumumab (DARA), a human anti-CD38 IgG1κ monoclonal
antibody, showed single agent activity in a phase 1/2 study of patients (pts) with relapsed or …