Structural characterization and anti-osteoporosis effects of polysaccharide purified from Eucommia ulmoides Oliver cortex based on its modulation on bone …

J Song, Y Zhang, Y Zhu, X Jin, L Li, C Wang… - Carbohydrate …, 2023 - Elsevier
EuOCP3, with a molecular weight of 38.1 kDa, is an acidic polysaccharide purified from
Eucommia ulmoides Oliver cortex. Herein, we determined that the main backbone of …

Structural elucidation and anti-osteoporosis activities of polysaccharides obtained from Curculigo orchioides

X Wang, M Zhang, D Zhang, X Wang, H Cao… - Carbohydrate …, 2019 - Elsevier
Curculigo orchioides, is a traditional Chinese medicine, is used in strengthening tendons
and bones. We evaluated the anti-osteoporosis activity of the crude polysaccharide (CO70) …

Structural characterization and osteoprotective effects of a polysaccharide purified from Achyranthes bidentata

D Zhang, C Wang, X Hou, C Yan - International journal of biological …, 2019 - Elsevier
Achyranthes bidentata has been traditionally used in China as a nature remedy for
osteoporosis; however, little is known about the osteoprotective effects of its …

Modulation of gut microbiota by chondroitin sulfate calcium complex during alleviation of osteoporosis in ovariectomized rats

Q Shen, C Zhang, X Qin, H Zhang, Z Zhang… - Carbohydrate …, 2021 - Elsevier
Although chondroitin sulfate calcium complex (CSCa) was claimed to have the bioactivity for
bone care in vitro, its anti-osteoporosis bioactivity was little reported in vivo. Here, the effects …

Anti-osteoporosis activity of a novel Achyranthes bidentata polysaccharide via stimulating bone formation

S Zhang, Q Zhang, D Zhang, C Wang, C Yan - Carbohydrate polymers, 2018 - Elsevier
Achyranthes bidentata is an important Traditional Chinese Medicine for the treatment of
osteoporosis. In this study, A. bidentata polysaccharide (ABPB), which was extracted with …

Morinda officinalis polysaccharide enable suppression of osteoclastic differentiation by exosomes derived from rat mesenchymal stem cells

P Wu, F Jiao, H Huang, D Liu, W Tang… - Pharmaceutical …, 2022 - Taylor & Francis
Abstract Context Morinda officinalis FC How.(MO)(Rubiaceae) can strengthen bone function.
Objective To examine the functional mechanism and effect of MO polysaccharides (MOPs) in …

[HTML][HTML] Orcinol glucoside improves senile osteoporosis through attenuating oxidative stress and autophagy of osteoclast via activating Nrf2/Keap1 and mTOR …

W Gong, M Liu, Q Zhang, Q Zhang, Y Wang… - … Medicine and Cellular …, 2022 - hindawi.com
Oxidative stress and autophagy play essential roles in the development of senile
osteoporosis which is characterized by disrupted osteoclastic bone resorption and …

Curculigo orchioides polysaccharide COP70-1 stimulates osteogenic differentiation of MC3T3-E1 cells by activating the BMP and Wnt signaling pathways

J Wang, J Yang, Z Tang, Y Yu, H Chen, Q Yu… - International Journal of …, 2023 - Elsevier
The crude polysaccharide CO70 isolated from Curculigo orchioides could alleviate
ovariectomy-induced osteoporosis in rats. To clarify the bioactive components, a new …

[HTML][HTML] Chondroitin Sulfate Alleviates Diabetic Osteoporosis and Repairs Bone Microstructure via Anti-Oxidation, Anti-Inflammation, and Regulating Bone …

SS Qi, ML Shao, Z Sun, SM Chen, YJ Hu… - Frontiers in …, 2021 - frontiersin.org
Diabetic osteoporosis (DOP) belongs to secondary osteoporosis caused by diabetes; it has
the characteristics of high morbidity and high disability. In the present study, we constructed …

Structural characterization of a novel oligosaccharide from Achyranthes bidentata and its anti-osteoporosis activities

C Wang, D Zhang, M Zhang, Y Jiao, K Jiang… - Industrial Crops and …, 2017 - Elsevier
Achyranthes bidentata Blume is one of the most frequently used medicinal herbs prescribed
for treatment of osteoporosis in China. This study describes the crude saccharide (AB90) …