In ovo vaccination with the Eimeria tenella EtMIC2 gene induces protective immunity against coccidiosis

X Ding, HS Lillehoj, RA Dalloul, W Min, T Sato… - Vaccine, 2005 - Elsevier
An Eimeria tenella microneme recombinant gene (EtMIC2) and encoded protein were
evaluated as potential vaccines against avian coccidiosis. In ovo inoculation with the EtMIC2 …

EMBRYO VACCINATION AGAINST EIMERIA TENELLA AND E. ACERVULINA INFECTIONS USING RECOMBINANT PROTEINS AND CYTOKINE ADJUVANTS

HS Lillehoj, X Ding, RA Dalloul, T Sato… - Journal of …, 2005 - meridian.allenpress.com
Avian coccidiosis is an intestinal disease caused by protozoa of the genus Eimeria. To
investigate the potential of recombinant protein vaccines to control coccidiosis, we cloned 2 …

Cloning, expression and evaluation of the efficacy of a recombinant Eimeria tenella sporozoite antigen in birds

BM Subramanian, R Sriraman, NH Rao, J Raghul… - Vaccine, 2008 - Elsevier
Eimeria infection in poultry is of significant economic interest worldwide. Development of a
cost-effective sub-unit vaccine that provides cross-protection may help reduce loss in poultry …

A DNA vaccine encoding a conserved Eimeria protein induces protective immunity against live Eimeria acervulina challenge

KD Song, HS Lillehoj, KD Choi, CH Yun, MS Parcells… - Vaccine, 2000 - Elsevier
Coccidiosis is caused by several distinct intestinal protozoa of Eimeria sp., and is
responsible for intestinal lesions and severe body weight loss in chickens. To develop a …

[HTML][HTML] Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high-level E. maxima challenge …

I Pastor-Fernández, S Kim, V Marugán-Hernández… - Parasites & …, 2020 - Springer
Background Poultry coccidiosis is a parasitic enteric disease with a highly negative impact
on chicken production. In-feed chemoprophylaxis remains the primary method of control, but …

Multi-epitope recombinant vaccine induces immunoprotection against mixed infection of Eimeria spp.

J Ding, W Qian, Q Liu, Q Liu - Parasitology research, 2012 - Springer
Immunity to Eimeria is species-specific, and chickens with immunity to one species of
Eimeria remain susceptible to other Eimeria species. This presents a major challenge in the …

Plant expressed EtMIC2 is an effective immunogen in conferring protection against chicken coccidiosis

K Sathish, R Sriraman, BM Subramanian, NH Rao… - Vaccine, 2011 - Elsevier
Coccidiosis is an economically important disease affecting poultry industry and remains one
of the major problems globally. Developing a cost effective sub-unit vaccine may help …

Resistance to Intestinal Coccidiosis Following DNA Immunization with the Cloned 3-1E Eimeria Gene Plus IL-2, IL-15, and IFN-γ

HS Lillehoj, X Ding, MA Quiroz, E Bevensee… - Avian …, 2005 - meridian.allenpress.com
A cloned Eimeria acervulina gene (3-1E) was used to vaccinate chickens in ovo against
coccidiosis, both alone and in combination with genes encoding interleukin (IL)-1, IL-2, IL-6 …

Construction of Eimeria tenella multi-epitope DNA vaccines and their protective efficacies against experimental infection

X Song, L Xu, R Yan, X Huang, X Li - Veterinary immunology and …, 2015 - Elsevier
The search for effective vaccines against chicken coccidiosis remains a challenge because
of the complex organisms with multiple life cycle stages of Eimeria. Combination of T-cell …

Induction of protective immunity against Eimeria tenella, Eimeria necatrix, Eimeria maxima and Eimeria acervulina infections using multivalent epitope DNA vaccines

X Song, Z Ren, R Yan, L Xu, X Li - Vaccine, 2015 - Elsevier
Avian coccidiosis is mostly caused by mixed infection of several Eimeria species under
natural conditions and immunity to avian coccidiosis is largely dependent on T-cell immune …