BendaEAM versus BEAM as conditioning regimen for ASCT in patients with relapsed lymphoma (BEB): a multicentre, randomised, phase 2 trial

F Keil, AMS Müller, A Berghold, R Riedl… - …, 2023 - thelancet.com
Background Replacement of carmustine (BCNU) in the BEAM regimen (BCNU, etoposide,
cytarabine, melphalan) with bendamustine (BendaEAM) before autologous stem cell …

Bendamustine, but not fludarabine, exhibits a low stem cell toxicity in vitro

M Schmidt-Hieber, A Busse, B Reufi, W Knauf… - Journal of cancer …, 2009 - Springer
Purpose We investigated the in vitro toxicity of bendamustine and fludarabine to
hematopoietic progenitors and stem cells from healthy donors. Methods Clonogenic agar …

Bendamustine, etoposide and dexamethasone to mobilize peripheral blood hematopoietic stem cells for autologous transplantation in patients with multiple myeloma

DJ Green, WI Bensinger, LA Holmberg… - Bone marrow …, 2016 - nature.com
Chemotherapeutic agents without cross-resistance to prior therapies may enhance PBSC
collection and improve patient outcomes by exacting a more potent direct antitumor effect …

Conditioning regimens: balancing efficacy and toxicity

TR Brooks, D Jagadeesh - Leukemia & Lymphoma, 2023 - Taylor & Francis
The remarkable evolution of hematopoietic stem cell transplant (HSCT) over the years
driven by the advances in donor selection, conditioning regimen, supportive care, GVHD …

Bendamustine in combination with fludarabine and rituximab: A novel nonmyeloablative conditioning for allogeneic stem cell transplantation (AST) in patients with …

IF Khouri, R Saliba, M Korbling, AM Alousi… - Journal of Clinical …, 2011 - ascopubs.org
e18511 Background: We previously reported the use of fludarabine, rituximab and
cyclophosphamide as a nonmyeloablative conditioning for lymphomas (Khouri et al, Blood …

Immunomodulatory effects of bendamustine in hematopoietic cell transplantation

J Stokes, MS Molina, EA Hoffman, RJ Simpson… - Cancers, 2021 - mdpi.com
Simple Summary Bendamustine is a chemotherapeutic agent used to treat a variety of
cancers. It has recently been used in the context of allogeneic hematopoietic cell …

Modified BEAM as conditioning regimen for lymphoma patients undergoing autologous hematopoietic stem cell transplantation

P Galieni, E Troiani, C Bigazzi, S Mazzotta… - Bone Marrow …, 2018 - nature.com
Over the last 30 years, BEAM has been the most widely used conditioning regimen before
autologous hematopoietic stem cell transplantation (auto-HSCT) for patients with Hodgkin …

Sequential intensive chemotherapy followed by autologous or allogeneic transplantation for refractory lymphoma

N Orfali, Y Jhanwar, C Koo, M Pasciolla… - Leukemia & …, 2021 - Taylor & Francis
We evaluate the safety of bendamustine as a bridge to stem cell transplantation (SCT) in
patients with relapsed/refractory lymphoma and residual disease after salvage therapy …

[PDF][PDF] Bendamustine-based conditioning prior to autologous stem cell transplantation is associated with high rate of febrile neutropenia and higher mortality

M Lucijanić, Ž Prka, O Jakšić, Z Mitrović… - American journal of …, 2019 - medlib.mef.hr
We have read the paper by Chantepie et al. 1 evaluating safety of benadamustine-based
conditioning prior to autologous stem cell transplantation (ASCT) with great interest. Authors …

[HTML][HTML] Bfr (bendamustine, fludarabine, rituximab) nonmyeloablative allogeneic conditioning: a novel regimen inducing immunosuppression without …

IF Khouri, W Wei, R Valverde, M Korbling, F Turturro… - Blood, 2013 - Elsevier
Background We previously reported the use of BFR, with phase 1 escalating daily doses of
70, 90, 110, or 130 mg/m 2 of bendamustine daily x 3 days prior to transplantation without …