Multidisciplinary research efforts in the field of drug delivery have led to the development of
a variety of drug delivery systems (DDS) designed for site-specific delivery of diagnostic and …

Advances in the delivery of targeted drug systems have evolved to enable highly regulated
site specific localization to subcellular organelles. Targeting therapeutics to individual …

Over the last half century, the delivery of pharmacologically active substances, such as
synthetic drugs, natural compounds, gene material and many other pharmaceutical …

To develop novel therapies for clinical treatments, it increasingly depends on sophisticated
delivery systems that facilitate the drugs entry into targeting cells. Profound understanding of …

This theme issue, edited by Hamm-Alvarez and Okamoto (University of Southern California),
brings together a collection of articles authored by experts working in the areas of …

Importance of the field: The last 10 years have seen a dramatic growth in understanding and
controlling how complex, drug-loaded (nano) structures, as well as pathogens, or …

Many drugs have been designed to act on intracellular targets and to affect intracellular
processes inside target cells. For the desired effects to be exerted, these drugs should …

Endocytosis and vesicular trafficking are cellular processes that regulate numerous
functions required to sustain life. From a translational perspective, they offer avenues to …

The movement of micro and macro molecules into and within a cell significantly governs
several of their pharmacokinetic and pharmacodynamic parameters, thus regulating the …

Efficient cellular delivery of biologically active molecules is one of the key factors that affect
the discovery and development of novel drugs. The plasma membrane is the first barrier that …