Chitosan/hydroxyapatite nanocomposite scaffolds to modulate osteogenic and inflammatory response

A Soriente, I Fasolino… - … Research Part A, 2022 - Wiley Online Library
Considerable attention has been given to the use of chitosan (CS)‐based materials
reinforced with inorganic bioactive signals such as hydroxyapatite (HA) to treat bone defects …

Osteoinductive and anti-inflammatory properties of chitosan-based scaffolds for bone regeneration

I Fasolino, MG Raucci, A Soriente, C Demitri… - Materials Science and …, 2019 - Elsevier
Current bone implants based on new biomaterials may cause a foreign body reaction (FBR)
around the implant itself thus prolonging the healing time following bone fractures. In this …

Biomimetic chitosan–nanohydroxyapatite composite scaffolds for bone tissue engineering

WW Thein-Han, RDK Misra - Acta biomaterialia, 2009 - Elsevier
We describe a comparative assessment of the structure–property–process relationship of
three-dimensional chitosan–nanohydroxyapatite (nHA) and pure chitosan scaffolds in …

Development of porous chitosan–gelatin/hydroxyapatite composite scaffolds for hard tissue‐engineering applications

C Isikli, V Hasirci, N Hasirci - Journal of tissue engineering and …, 2012 - Wiley Online Library
Composite scaffolds prepared from natural polymers and hydroxyapatite (HA) are expected
to have enhanced osteoconductive properties and as a result gained much attention in …

Novel chitosan/agarose/hydroxyapatite nanocomposite scaffold for bone tissue engineering applications: Comprehensive evaluation of biocompatibility and …

P Kazimierczak, A Benko, M Nocun… - International journal of …, 2019 - Taylor & Francis
Background Nanocomposites produced by reinforcement of polysaccharide matrix with
nanoparticles are widely used in engineering of biomaterials. However, clinical applications …

Chitosan/hydroxyapatite hybrid scaffold for bone tissue engineering

V Brun, C Guillaume, S Mechiche Alami… - Bio-medical …, 2014 - content.iospress.com
BACKGROUND: To favor regeneration following critical bone defect, a combination of
autologous bone graft and biomaterials is currently used. Major drawbacks of such …

In vivo study of chitosan-natural nano hydroxyapatite scaffolds for bone tissue regeneration

JS Lee, SD Baek, J Venkatesan, I Bhatnagar… - International Journal of …, 2014 - Elsevier
Significant development has been achieved with bioceramics and biopolymer scaffolds in
the construction of artificial bone. In the present study, we have developed and compared …

Fabrication of cancellous biomimetic chitosan‐based nanocomposite scaffolds applying a combinational method for bone tissue engineering

Z Jamalpoor, H Mirzadeh, MT Joghataei… - … research Part A, 2015 - Wiley Online Library
The aim of this study was to mimic the specific structure of bone and fabricate a biomimetic
nano‐hydroxyapatite (HA)/chitosan (Cs)/gelatin scaffolds using combination of particle …

Synthesis, characterization and in-vitro behavior of natural chitosan-hydroxyapatite-diopside nanocomposite scaffold for bone tissue engineering

S Shemshad, S Kamali, A Khavandi… - International Journal of …, 2019 - Taylor & Francis
Composite materials based on a combination of biodegradable polymers and bioactive
ceramics, including chitosan and hydroxyapatite are discussed as suitable materials for …

Biomedical potential of chitosan/HA and chitosan/β-1, 3-glucan/HA biomaterials as scaffolds for bone regeneration—A comparative study

A Przekora, K Palka, G Ginalska - Materials Science and Engineering: C, 2016 - Elsevier
The aim of this work was to compare biomedical potential of chitosan/hydroxyapatite
(chit/HA) and novel chitosan/β-1, 3-glucan/hydroxyapatite (chit/glu/HA) materials as …