MicroRNA Let-7d Mediated Mesenchymal Stem Cell Exosomes Against Idiopathic Pulmonary Fibrosis Through Epithelial-Mesenchymal Transition Progress

J Liu, X Han, M Gu, Q Zhao, Q Li, X Liu - 2024 - researchsquare.com
Background Mesenchymal stem cells (MSCs) commonly affect idiopathic pulmonary fibrosis
(IPF) through the epithelial-mesenchymal transition (EMT) process. And exosomes of MSCs …

[HTML][HTML] microRNA-186 in extracellular vesicles from bone marrow mesenchymal stem cells alleviates idiopathic pulmonary fibrosis via interaction with SOX4 and …

J Zhou, Y Lin, X Kang, Z Liu, W Zhang, F Xu - Stem cell research & therapy, 2021 - Springer
Background Previous reports have identified that human bone marrow mesenchymal stem
cell-derived extracellular vesicles (BMSC-EVs) with their cargo microRNAs (miRNAs) are a …

Mesenchymal stem cell‐derived extracellular vesicles suppress the fibroblast proliferation by downregulating FZD6 expression in fibroblasts via micrRNA‐29b‐3p in …

X Wan, S Chen, Y Fang, W Zuo, J Cui… - Journal of Cellular …, 2020 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF), a progressive and fatal lung disease, usually leads to an
irreversible distortion of the pulmonary structure. The functional roles of bone marrow …

[HTML][HTML] Exosomal miR-17-5p from human embryonic stem cells prevents pulmonary fibrosis by targeting thrombospondin-2

Q Liu, Y Bi, S Song, K Zhu, X Qiao, H Wang… - Stem Cell Research & …, 2023 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible
lung disease characterized by pulmonary fibrosis and lung dysfunction, ultimately leading to …

microRNA-130b-3p delivery by mesenchymal stem cells-derived exosomes confers protection on acute lung injury

X Wang, J Feng, H Dai, J Mo, B Luo, C Luo… - …, 2022 - Taylor & Francis
Objective Researchers have investigated miR-130b-3p in lung disease pathology, such as
lung fibrosis. The present study was performed to elucidate the miR-130b-3p-involved …

Mesenchymal stem cells-derived exosomes carrying microRNA-30b confer protection against pulmonary fibrosis by downregulating Runx1 via Spred2

L Zhu, Y Xu, J Wang, Y Zhang, J Zhou, H Wu - Molecular Genetics and …, 2024 - Springer
Idiopathic pulmonary fibrosis (IPF) is a chronic pulmonary fibrosis disease that is fatal.
Mesenchymal stem cells (MSCs)-secreted exosomes (exos) have been linked to improving …

[HTML][HTML] The extracellular matrix enriched with exosomes for the treatment on pulmonary fibrosis in mice

Y Yu, X Liu, Z Zhao, Z Xu, Y Qiao, Y Zhou… - Frontiers in …, 2021 - frontiersin.org
Pulmonary fibrosis (PF) is a severe respiratory disease caused by lung microenvironment
changes. TGF-β/Smad3 signaling pathway plays a critical role in the fibrotic process …

Exosomal miR-218 derived from mesenchymal stem cells inhibits endothelial-to-mesenchymal transition by epigenetically modulating of BMP2 in pulmonary fibrosis

Y Zhao, L Du, J Sun, X Wang, Z Cong, S Chen… - Cell Biology and …, 2023 - Springer
Endothelial-to-mesenchymal transition (EndMT), the process by which endothelial cells lose
their characteristics and acquire mesenchymal phenotypes, participates in the pathogenic …

Exosomal miRNA Let‐7 from menstrual blood‐derived endometrial stem cells alleviates pulmonary fibrosis through regulating mitochondrial DNA damage

L Sun, M Zhu, W Feng, Y Lin, J Yin… - … medicine and cellular …, 2019 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a prototype of chronic, progressive, and fibrotic lung
disease with high morbidity and high mortality. Menstrual blood‐derived stem cells …

Mesenchymal Stem Cell-Derived Exosomes Attenuate SiO2-Induced Pulmonary Fibrosis by Inhibiting Pulmonary Fibroblast Transdifferentiation Through miR-99a

P Li, X Hao, X Gao, J Liu, Q Zhang, Y Wang… - Available at SSRN … - papers.ssrn.com
Background: Silicosis is one of the most prevalent and fatal occupational diseases
worldwide, with unsatisfactory clinical outcomes. This study aimed to investigate the …