ABSTRACT Tetherin (BST-2 or CD317) is an interferon-inducible transmembrane protein
that inhibits virus release from infected cells. To determine the extent of sequence variation …

Tetherin (BST-2 or CD317) is an interferon-inducible cellular factor that prevents the
detachment of enveloped viruses from infected cells. The primate lentiviruses have evolved …

Summary Tetherin (BST-2 or CD317) is an interferon-inducible transmembrane protein that
inhibits virus release from infected cells. Whereas HIV-1 Vpu and HIV-2 Env counteract …

The host restriction factor tetherin inhibits virion release from infected cells and poses a
significant barrier to successful zoonotic transmission of primate lentiviruses to humans …

Tetherin, also known as BST2, CD317 or HM1. 24, was recently identified as an interferon-
inducible host–cell factor that interferes with the detachment of virus particles from infected …

The Vpu accessory gene that originated in the primate lentiviral lineage leading to human
immunodeficiency virus type 1 is an antagonist of human tetherin/BST-2 restriction. Most …

Tetherin/BST-2 is a host-encoded protein that restricts a wide diversity of viruses at the stage
of virion release. However, viruses have evolved antagonists of Tetherin, including the Vpu …

Most simian immunodeficiency viruses use their Nef protein to antagonize the host
restriction factor tetherin. A deletion in human tetherin confers Nef resistance, representing a …

Although Nef is the viral gene product used by most simian immunodeficiency viruses to
overcome restriction by tetherin, this activity was acquired by the Vpu protein of HIV-1 group …

Primate lentiviruses including human immunodeficiency virus type 1 (HIV-1) and simian
immunodeficiency viruses (SIVs) evolved through the acquisition of antagonists against …