Amyotrophic lateral sclerosis (ALS) is a neurodegenerative neuromuscular disease that
affects motor neurons controlling voluntary muscles. Survival is usually 2–5 years after …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the degeneration of motor neurons, and there is currently a lack of reliable diagnostic …

Amyotrophic lateral sclerosis (ALS) is a late-onset neurodegenerative condition, most widely
characterized by the selective vulnerability of motor neurons and the poor life expectancy of …

Objective To evaluate the classifier performance, clinical and biochemical correlations of
cerebrospinal fluid (CSF) levels of the chitinase proteins Chitotriosidase-1 (CHIT1) …

Objective Amyotrophic lateral sclerosis (ALS) is a complex disease with numerous
pathological mechanisms resulting in a heterogeneous patient population. Using …

Background Potential biomarkers to aid diagnosis and therapy need to be identified for
Amyotrophic Lateral Sclerosis, a progressive motor neuronal degenerative disorder. The …

Objective The neurodegenerative disease, amyotrophic lateral sclerosis (ALS), is a
heterogeneous clinical syndrome involving multiple molecular pathways. The development …

Objectives Neurochemical markers of amyotrophic lateral sclerosis (ALS) that reflect
underlying disease mechanisms might help in diagnosis, staging and prediction of outcome …

Objective To evaluate the CSF levels of chitinase proteins during the presymptomatic and
early symptomatic phases of amyotrophic lateral sclerosis (ALS). Methods CSF samples …

Neuroinflammation significantly contributes to Amyotrophic Lateral Sclerosis (ALS)
pathology. In lieu of this, reports of elevated chitinase levels in ALS are interesting, as they …