Objective Inflammation is a key pathological hallmark in amyotrophic lateral sclerosis (ALS),
which seems to be linked to the disease progression. It is not clear what the added …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder which is
characterized by progressive degeneration of the motor system. Typically, the disease starts …

In most patients with multiple sclerosis, the disease initiates with a first attack or clinically
isolated syndrome. At this phase, magnetic resonance imaging is an important predictor of …

A diagnostic biomarker for ALS would permit early intervention with disease-modifying
therapies while a biomarker for disease activity could accelerate the pace of drug discovery …

Objectives: In amyotrophic lateral sclerosis (ALS) the pathological determinants of disease
progression remain poorly understood. We aimed to identify a characteristic CSF protein …

Background and Objectives Multiple sclerosis (MS) is an autoimmune disease confined in
the CNS, and its course is frequently subtle and variable. Therefore, predictive biomarkers …

Idiopathic normal-pressure hydrocephalus (iNPH) is an uncommon neurological disorder
with no known pathological hallmarks. INPH may share common degenerative pathways …

Neurochemical biomarkers in amyotrophic lateral sclerosis : Current Opinion in Neurology
Neurochemical biomarkers in amyotrophic lateral sclerosis : Current Opinion in Neurology Log …

Serum neurofilament light chain (NfL) and chitinase 3-like 1 (CHI3L1, also called YKL-40)
concentrations are attractive candidate biomarkers for neurodegenerative disorders, which …

Neuroaxonal damage is a feature of various neurodegenerative diseases including
amyotrophic lateral sclerosis (ALS). Phosphorylated neurofilament heavy chain (pNfH) is a …