Abstract Human Leukocyte Antigens (HLA) matching at the serological level used to serve
as the measure of histocompatibility between organ donors and recipients. With …

Summary Human Leukocyte Antigen (HLA) diversity is the key driver of alloimmune
responses. Ideally, patients would receive an allograft that is fully matched at the allelic …

Over the past decade, high HLA epitope mismatch scores have been associated with inferior
transplant outcomes using several tools, of which HLAMatchmaker is most well-known. This …

The development of de novo donor-specific antibodies is related to the poor matching of the
human leukocyte antigen (HLA) between donor and recipient, which leads to dismal clinical …

Significant progress has been made in developing computational HLA immunogenicity
algorithms that offer exciting opportunities for a more rational approach to determining the …

Conclusion Recent studies that have evaluated HLA molecular mismatch in the context of
immunosuppression minimization are examples of how more precise measurements of …

Human leukocyte Antigen (HLA) mismatching leads to severe complications after solid‐
organ transplantation and hematopoietic stem‐cell transplantation. The alloreactive …

Abstract The International Registry of Antibody‐Defined HLA Epitopes (http://www.
epregistry. com. br) has been recently established as a tool to understand humoral …

HLA mismatching is an important risk factor for antibody-mediated rejection and transplant
failure. With the realization HLA antibodies recognize epitopes rather than antigens, it has …

HLAMatchmaker is a computer algorithm that determines HLA compatibility at the structural
level. Donor–recipient histocompatibility is assessed with polymorphic amino acid …