Macrophage-mediated cancer drug delivery
Cell-mediated drug delivery systems have attracted significant research interest in the past
years owing to their superior properties such as excellent biocompatibility, potential long …
years owing to their superior properties such as excellent biocompatibility, potential long …
Targeting tumor associated macrophages (TAMs) via nanocarriers
Recruitment of inflammatory cells to tumor has been well documented, with the most
frequent inhabitants being macrophages termed as tumor associated macrophages,(TAMs) …
frequent inhabitants being macrophages termed as tumor associated macrophages,(TAMs) …
Tumor-associated macrophages in nanomaterial-based anti-tumor therapy: as target spots or delivery platforms
Targeting tumor-associated macrophages (TAMs) has emerged as a promising approach in
cancer therapy. This article provides a comprehensive review of recent advancements in the …
cancer therapy. This article provides a comprehensive review of recent advancements in the …
Engineering macrophages for cancer immunotherapy and drug delivery
Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …
Nanoparticle‐laden macrophages for tumor‐tropic drug delivery
Macrophages hold great potential in cancer drug delivery because they can sense
chemotactic cues and home to tumors with high efficiency. However, it remains a challenge …
chemotactic cues and home to tumors with high efficiency. However, it remains a challenge …
Macrophages associated with tumors as potential targets and therapeutic intermediates
S Vinogradov, G Warren, X Wei - Nanomedicine, 2014 - Taylor & Francis
Tumor-associated macrophages (TAMs) form approximately 50% of tumor mass. TAMs were
shown to promote tumor growth by suppressing immunocompetent cells, inducing …
shown to promote tumor growth by suppressing immunocompetent cells, inducing …
[HTML][HTML] Use of macrophage as a Trojan horse for cancer nanotheranostics
Y Qi, X Yan, T Xia, S Liu - Materials & Design, 2021 - Elsevier
Nano-based cancer theranostics are often not as effective as expected due to the low
accumulation of nanoparticles in tumors, and cell-aided strategies may represent a rescue to …
accumulation of nanoparticles in tumors, and cell-aided strategies may represent a rescue to …
Tumor Associated Macrophages and TAMs‐Based Anti‐Tumor Nanomedicines
Y Cheng, S Song, P Wu, B Lyu, M Qin… - Advanced …, 2021 - Wiley Online Library
As an important part of tumor microenvironment, tumor associated macrophages (TAMs)
play a vital role in the occurrence, development, invasion, and metastasis of many malignant …
play a vital role in the occurrence, development, invasion, and metastasis of many malignant …
Nanoparticles targeting tumor-associated macrophages: A novel anti-tumor therapy
S Chen, F Qin, M Wang, Y Wei, Z Qian, X Wei - Nano Research, 2021 - Springer
The immunosuppressive tumor microenvironment (TME) is crucial in the occurrence of
tumorigenesis, metastasis, and drug resistance. Among all stromal cells, tumor-associated …
tumorigenesis, metastasis, and drug resistance. Among all stromal cells, tumor-associated …
Tumor-Associated Macrophage Targeting of Nanomedicines in Cancer Therapy
The tumor microenvironment (TME) is pivotal in tumor growth and metastasis, aligning with
the “Seed and Soil” theory. Within the TME, tumor-associated macrophages (TAMs) play a …
the “Seed and Soil” theory. Within the TME, tumor-associated macrophages (TAMs) play a …