Cell-mediated drug delivery systems have attracted significant research interest in the past
years owing to their superior properties such as excellent biocompatibility, potential long …

Recruitment of inflammatory cells to tumor has been well documented, with the most
frequent inhabitants being macrophages termed as tumor associated macrophages,(TAMs) …

Targeting tumor-associated macrophages (TAMs) has emerged as a promising approach in
cancer therapy. This article provides a comprehensive review of recent advancements in the …

Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …

Macrophages hold great potential in cancer drug delivery because they can sense
chemotactic cues and home to tumors with high efficiency. However, it remains a challenge …

Tumor-associated macrophages (TAMs) form approximately 50% of tumor mass. TAMs were
shown to promote tumor growth by suppressing immunocompetent cells, inducing …

Nano-based cancer theranostics are often not as effective as expected due to the low
accumulation of nanoparticles in tumors, and cell-aided strategies may represent a rescue to …

As an important part of tumor microenvironment, tumor associated macrophages (TAMs)
play a vital role in the occurrence, development, invasion, and metastasis of many malignant …

The immunosuppressive tumor microenvironment (TME) is crucial in the occurrence of
tumorigenesis, metastasis, and drug resistance. Among all stromal cells, tumor-associated …

The tumor microenvironment (TME) is pivotal in tumor growth and metastasis, aligning with
the “Seed and Soil” theory. Within the TME, tumor-associated macrophages (TAMs) play a …