Our objectives were to examine changes in endometrial and luteal gene expression during
estrus, diestrus, pregnancy and treatments to induce luteolysis and putatively induce …

Our understanding of the temporal changes in endometrial and luteal gene transcripts
related to the actions of oxytocin and prostaglandin during early equine pregnancy is …

Oxytocin (OXT) has been used to prolong the luteal phase in mares, but its mechanism of
action is unknown. The aim of this study was to evaluate the effect of chronic exogenous …

Progestin concentration in plasma during the early luteal phase is crucial for endometrial
function and conceptus development. We hypothesized that periovulatory gonadotrophin …

In the horse, it is still unclear if and to what extent low progestin concentration contributes to
early conceptus loss. In the present study, we have investigated if reduced or elevated …

A positive-feedback loop between luteal oxytocin and uterine prostaglandin F2α (PGF) is a
major signal for luteolysis in ruminants. Likewise, uterine PGF causes luteolysis in mares …

The objectives were to:(1) evaluate the efficacy of varying intervals of oxytocin administration
in preventing luteolysis in mares;(2) examine PGF2α release in mares experiencing …

2. Materials and Methods Mares used in this study ranged from 6 to 18 years old and
weighed 300 to 500 kg. All animal procedures were approved and conducted following the …

Endometrial oxytocin receptors (OXTR) and prostaglandin-endoperoxide synthase 2
(PTGS2) are central components of the luteolytic pathway in cyclic mares, and their …

In most mammalian species, progestins have a major function in maintaining pregnancy. In
humans, the physiologic initiation of parturition bears similarities with inflammatory …