No single effective therapy for alcohol abuse has been found, despite it being a serious
sociological and economic problem for hundreds of years. It seems difficult to find a single …

Alcoholism, a major public health problem throughout the world, causes enormous damage
to health and quality of life and undermines the well‐being of families and society. It is …

Patients who suffer from alcohol use disorders (AUDs) usually go through various socio-
behavioral and pathophysiological changes that take place in the brain and other organs …

Few medications for treating alcohol dependence exist. Greater partnership is needed
between academia and the pharmaceutical industry to develop, licence and market …

Compared to other medical disorders, including other brain diseases, the number of
medications approved for alcohol use disorder (AUD) is very small. Disulfiram, naltrexone …

Introduction: At present, the substances acamprosate, naltrexone and disulfiram are
available for pharmacotherapy in alcohol dependence, but clinical studies found only …

Alcohol dependence represents a chronic, relapsing condition with a multifactorial aetiology
that includes genetic, neurobiological, psychological, and environmental components …

Research on the treatment of alcoholism has gained significant ground over the past 40
years. Studies such as the National Institute on Alcohol Abuse and Alcoholism's Project …

More than 76 million people world‐wide are estimated to have diagnosable alcohol use
disorders (AUDs)(alcohol abuse or dependence), making these disorders a major global …

This article is part of a Festschrift commemorating the 50th anniversary of the National
Institute on Alcohol Abuse and Alcoholism (NIAAA). Established in 1970, first as part of the …