Very few studies have comprehensively defined the genetic and environmental influences
on body fat storage in the arms and legs and their association with diabetes, especially in …

Central obesity, measured by waist circumference (WC) or waist-hip ratio (WHR), is a marker
of body fat distribution. Although obesity disproportionately affects minority populations, few …

Results: Of the 17 WHR loci, eight single-nucleotide polymorphisms (SNPs) located in four
loci were replicated in the sex-combined or sex-stratified meta-analyses. Two of these eight …

The thrifty genotype hypothesis initiated speculation that feast and famine cycling throughout
history may have led to group‐specific alterations of the human genome, thereby …

Objective: Although differences in body composition parameters among African American
(AA), Hispanic American (HA) and European American (EA) children are well documented …

We aimed to identify the independent associations of genomic ancestry and education level
with abdominal fat distributions in the 1982 Pelotas birth cohort study, Brazil. In 2,890 …

Background: The Roma people are particularly vulnerable to developing obesity and related
diseases, due to their social and ethnic backgrounds. However, little is known about the …

Objective: Increased fat infiltration in skeletal muscle has been associated with diabetes.
Quantitative computed tomography (QCT) can be used to measure muscle density, which …

OBJECTIVE: To conduct a full genome search for genes potentially influencing two related
phenotypes: body mass index (BMI, kg/m 2) and percent body fat (PBF) from bioelectric …

Objective: Recent genome-wide association studies (GWAS) have identified multiple novel
loci associated with adiposity in European-derived study populations. Limited study of these …