DNA methylation is important for the epigenetic regulation of gene expression and plays a
critical role in mammalian development. However, the dynamic regulation of genome-wide …

Background DNA methylation is an epigenetic regulatory form that plays an important role in
regulating the gene expression and the tissues development.. However, DNA methylation …

DNA methylation is a key epigenetic modification in mammals and plays important roles in
muscle development. We sampled longissimus dorsi muscle (LDM) from a well-known elite …

Differentiation-related DNA methylation is receiving increasing attention, partly owing to
new, whole-genome analyses. These revealed that cell type-specific differential methylation …

Remodelling the methylome is a hallmark of mammalian development and cell
differentiation. However, current knowledge of DNA methylation dynamics in human tissue …

Background Uncovering mechanisms of epigenome evolution is an essential step towards
understanding the evolution of different cellular phenotypes. While studies have confirmed …

Myogenic cell cultures derived from muscle biopsies are excellent models for human cell
differentiation. We report the first comprehensive analysis of myogenesis-specific DNA hyper …

Abstract N 6-methyladenosine (m 6 A) represents the most abundantly occurring mRNA
modification and is involved in the regulation of skeletal muscle development. However, the …

Transcriptome wide changes in human skeletal muscle after acute (anabolic) and chronic
resistance exercise (RE) induced hypertrophy have been extensively determined in the …

Background DNA methylation is an important epigenetic modification that is essential for
epigenetic gene regulation in development and disease. To date, the genome-wide DNA …