Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns
DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …
regulation and development. DNA methylation patterns are established during early …
Genome-wide DNA methylation profiles changes associated with constant heat stress in pigs as measured by bisulfite sequencing
Y Hao, Y Cui, X Gu - Scientific Reports, 2016 - nature.com
Heat stress affects muscle development and meat quality in food animals; however, little is
known regarding its regulatory mechanisms at the epigenetic level, such as via DNA …
known regarding its regulatory mechanisms at the epigenetic level, such as via DNA …
Dynamic changes in the human methylome during differentiation
DNA methylation is a critical epigenetic regulator in mammalian development. Here, we
present a whole-genome comparative view of DNA methylation using bisulfite sequencing of …
present a whole-genome comparative view of DNA methylation using bisulfite sequencing of …
DNA methylation QTL mapping across diverse human tissues provides molecular links between genetic variation and complex traits
M Oliva, K Demanelis, Y Lu, M Chernoff, F Jasmine… - Nature …, 2023 - nature.com
Studies of DNA methylation (DNAm) in solid human tissues are relatively scarce; tissue-
specific characterization of DNAm is needed to understand its role in gene regulation and its …
specific characterization of DNAm is needed to understand its role in gene regulation and its …
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle
We integrate comeasured gene expression and DNA methylation (DNAme) in 265 human
skeletal muscle biopsies from the FUSION study with> 7 million genetic variants and eight …
skeletal muscle biopsies from the FUSION study with> 7 million genetic variants and eight …
DNA methylation reprogramming of functional elements during mammalian embryonic development
DNA methylation plays important roles during development. However, the DNA methylation
reprogramming of functional elements has not been fully investigated during mammalian …
reprogramming of functional elements has not been fully investigated during mammalian …
Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage
L Chavez, J Jozefczuk, C Grimm, J Dietrich… - Genome …, 2010 - genome.cshlp.org
The generation of genome-wide data derived from methylated DNA immunoprecipitation
followed by sequencing (MeDIP-seq) has become a major tool for epigenetic studies in …
followed by sequencing (MeDIP-seq) has become a major tool for epigenetic studies in …
DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity
Skeletal muscle tissue demonstrates global hypermethylation with age. However,
methylome changes across the time-course of differentiation in aged human muscle derived …
methylome changes across the time-course of differentiation in aged human muscle derived …
Methylome Dynamics of Bovine Gametes and in vivo Early Embryos
DNA methylation undergoes drastic fluctuation during early mammalian embryogenesis.
The dynamics of global DNA methylation in bovine embryos, however, have mostly been …
The dynamics of global DNA methylation in bovine embryos, however, have mostly been …
DNA methylation patterning and the regulation of beta cell homeostasis
N Parveen, S Dhawan - Frontiers in Endocrinology, 2021 - frontiersin.org
Pancreatic beta cells play a central role in regulating glucose homeostasis by secreting the
hormone insulin. Failure of beta cells due to reduced function and mass and the resulting …
hormone insulin. Failure of beta cells due to reduced function and mass and the resulting …