Frontotemporal dementia (FTD) is a devastating neurodegenerative disease characterized
by a rapid decline in behavioural, language, and motor abilities. Advances in the …

Background Advances in the understanding of the pathophysiology of frontotemporal
dementia (FTD) and related disorders, along with the development of novel candidate …

Recent advances in the understanding of frontotemporal dementia (FTD) and subsequently,
the development of novel disease modifying treatments, has stimulated the need for tools to …

Background: Previous studies suggest that brain atrophy can not only be defined by its
morphological extent, but also by the cerebral blood flow (CBF) within a certain area of the …

Purpose The clinical utility of FDG-PET in diagnosing frontotemporal dementia (FTD) has
been well demonstrated over the past decades. On the contrary, the diagnostic value of …

Objectives: To test if arterial spin labeling (ASL) MRI could detect a pattern of hypoperfusion
in frontotemporal dementia (FTD) vs cognitively normal (CN) control subjects; to determine …

Arterial Spin Labeling (ASL) is a non invasive perfusion imaging technique which has
shown great diagnosis potential in dementia. However, it has never been applied to …

Genetic forms of frontotemporal dementia are most commonly due to mutations in three
genes, C9orf72, GRN or MAPT, with presymptomatic carriers from families representing …

Objective To investigate arterial spin labeling (ASL)-MRI for the early diagnosis of and
differentiation between the two most common types of presenile dementia: Alzheimer's …

The ability of arterial spin labeling (ASL) to detect perfusion abnormalities in clinical
populations, such as frontotemporal dementia, can be limited by poor signal to noise and …