[HTML][HTML] Brucella abortus Proliferates in Decidualized and Non-Decidualized Human Endometrial Cells Inducing a Proinflammatory Response

L Zavattieri, MC Ferrero, IM Alonso Paiva, AD Sotelo… - Pathogens, 2020 - mdpi.com
Brucella spp. have been associated with abortion in humans and animals. Although the
mechanisms involved are not well established, it is known that placental Brucella infection is …

Proinflammatory Response of Human Trophoblastic Cells to Brucella abortus Infection and upon Interactions with Infected Phagocytes

AG Fernández, MC Ferrero, MS Hielpos… - Biology of …, 2016 - academic.oup.com
Trophoblasts are targets of infection by Brucella spp. but their role in the pathophysiology of
pregnancy complications of brucellosis is unknown. Here we show that Brucella abortus …

[HTML][HTML] Immune Responses Potentially Involved in the Gestational Complications of Brucella Infection

L Zavattieri, F Muñoz González, MC Ferrero, PC Baldi - Pathogens, 2023 - mdpi.com
Infection by Brucella species in pregnant animals and humans is associated with an
increased risk of abortion, preterm birth, and transmission of the infection to the offspring …

Tumor necrosis factor alpha contributes to inflammatory pathology in the placenta during Brucella abortus infection

AY Tsai, MX Byndloss, N Seyffert, MG Winter… - Infection and …, 2022 - Am Soc Microbiol
Research on Brucella pathogenesis has focused primarily on its ability to cause persistent
intracellular infection of the mononuclear phagocyte system. At these sites, Brucella abortus …

Modulation of the Bovine Trophoblastic Innate Immune Response by Brucella abortus

AV Carvalho Neta, APR Stynen, TA Paixao… - Infection and …, 2008 - Am Soc Microbiol
Brucellosis is still a widespread zoonotic disease. Very little is known about the interaction
between Brucella abortus and trophoblastic cells, which is essential for better understanding …

Infection by Brucella melitensis or Brucella papionis modifies essential physiological functions of human trophoblasts

KB García‐Méndez, SM Hielpos… - Cellular …, 2019 - Wiley Online Library
Brucellosis is a zoonosis caused by bacteria of the Brucella genus. In ruminants, brucellosis
causes abortion, followed by chronic infection and secretion of bacteria in milk. In humans, it …

Novel Replication Profiles of Brucella in Human Trophoblasts Give Insights Into the Pathogenesis of Infectious Abortion

D O'Callaghan - The Journal of infectious diseases, 2013 - academic.oup.com
Many infectious agents cause abortion in humans and in animals. In this issue of the Journal
of Infectious Diseases, an article by Salcedo et al [1] describes the behavior of Brucella …

Administration of Exogenous Progesterone Protects Against Brucella abortus Infection–Induced Inflammation in Pregnant Mice

J Ren, H Hou, W Zhao, J Wang… - The Journal of Infectious …, 2021 - academic.oup.com
Progesterone has been recognized as essential for the establishment and maintenance of
pregnancy, and is typically known as an immunosuppressive agent. However, its effects on …

[HTML][HTML] Kinetics of Placental Infection by Different Smooth Brucella Strains in Mice

I Poveda-Urkixo, GA Ramírez, MJ Grilló - Pathogens, 2022 - mdpi.com
Abortion and reproductive failures induced by Brucella are the main symptoms of animal
brucellosis. Laboratory animal models are essential tools of research to study the Brucella …

[HTML][HTML] Brucella suis vaccine strain S2-infected immortalized caprine endometrial epithelial cell lines induce non-apoptotic ER-stress

X Wang, P Lin, Y Yin, J Zhou, L Lei, X Zhou… - Cell Stress and …, 2015 - Elsevier
Brucella, which is regarded as an intracellular pathogen responsible for a zoonotic disease
called brucellosis, survives and proliferates within several types of phagocytic and non …