Biomaterial-based approaches to engineering immune tolerance
AE Emerson, EM Slaby, SC Hiremath… - Biomaterials Science, 2020 - pubs.rsc.org
The development of biomaterial-based therapeutics to induce immune tolerance holds great
promise for the treatment of autoimmune diseases, allergy, and graft rejection in …
promise for the treatment of autoimmune diseases, allergy, and graft rejection in …
Biomaterial strategies for selective immune tolerance: advances and gaps
ST Carey, C Bridgeman, CM Jewell - Advanced Science, 2023 - Wiley Online Library
Autoimmunity and allergies affect a large number of people across the globe. Current
approaches to these diseases target cell types and pathways that drive disease, but these …
approaches to these diseases target cell types and pathways that drive disease, but these …
Cell and biomaterial delivery strategies to induce immune tolerance
BL Scotland, JR Shaw, S Dharmaraj, N Caprio… - Advanced Drug Delivery …, 2023 - Elsevier
The prevalence of immune-mediated disorders, including autoimmune conditions and
allergies, is steadily increasing. However, current therapeutic approaches are often non …
allergies, is steadily increasing. However, current therapeutic approaches are often non …
Transplantation immune responses: Biology, challenges, and opportunities using biomaterials
The organs or cells transplantation is well-established in clinics. However, despite the
increasing success rates and the broadening of various transplantation techniques, a key …
increasing success rates and the broadening of various transplantation techniques, a key …
Tissue‐Targeted Drug Delivery Strategies to Promote Antigen‐Specific Immune Tolerance
Y Rui, HB Eppler, AA Yanes… - Advanced healthcare …, 2023 - Wiley Online Library
During autoimmunity or organ transplant rejection, the immune system attacks host or
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …
In vivo reprogramming of immune cells: technologies for induction of antigen-specific tolerance
Technologies that induce antigen-specific immune tolerance by mimicking naturally
occurring mechanisms have the potential to revolutionize the treatment of many immune …
occurring mechanisms have the potential to revolutionize the treatment of many immune …
Engineering immune tolerance with biomaterials
Autoimmune diseases, rejection of transplanted organs and grafts, chronic inflammatory
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …
Engineering vaccines and niches for immune modulation
Controlled modulation of immune response, especially the balance between
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …
[PDF][PDF] Engineering tolerance using biomaterials to target and control antigen presenting cells
LH Tostanoski, EA Gosselin, CM Jewell - Discov. Med, 2016 - jewell.umd.edu
Autoimmune diseases occur when cells of the adaptive immune system incorrectly
recognize and attack “self” tissues. Importantly, the proliferation and differentiation of these …
recognize and attack “self” tissues. Importantly, the proliferation and differentiation of these …
Biomaterial strategies for immunomodulation
Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …
importance for diverse biomedical applications, such as the development of new vaccines …