[HTML][HTML] Multimodality imaging-based characterization of regional material properties in a murine model of aortic dissection

MR Bersi, VA Acosta Santamaría, K Marback… - Scientific reports, 2020 - nature.com
Chronic infusion of angiotensin-II in atheroprone (ApoE−/−) mice provides a reproducible
model of dissection in the suprarenal abdominal aorta, often with a false lumen and …

A mechanistic model on the role of “radially-running” collagen fibers on dissection properties of human ascending thoracic aorta

S Pal, A Tsamis, S Pasta, A D'Amore, TG Gleason… - Journal of …, 2014 - Elsevier
Aortic dissection (AoD) is a common condition that often leads to life-threatening
cardiovascular emergency. From a biomechanics viewpoint, AoD involves failure of load …

Fluid–structure interaction simulations of patient-specific aortic dissection

K Bäumler, V Vedula, AM Sailer, J Seo, P Chiu… - … and modeling in …, 2020 - Springer
Credible computational fluid dynamic (CFD) simulations of aortic dissection are challenging,
because the defining parallel flow channels—the true and the false lumen—are separated …

Co-localization of microstructural damage and excessive mechanical strain at aortic branches in angiotensin-II-infused mice

L Aslanidou, M Ferraro, G Lovric, MR Bersi… - … and modeling in …, 2020 - Springer
Animal models of aortic aneurysm and dissection can enhance our limited understanding of
the etiology of these lethal conditions particularly because early-stage longitudinal data are …

Differential propensity of dissection along the aorta

E Ban, C Cavinato, JD Humphrey - Biomechanics and modeling in …, 2021 - Springer
Aortic dissections progress, in part, by delamination of the wall. Previous experiments on cut-
open segments of aorta demonstrated that fluid injected within the wall delaminates the …

Regional finite strains in an angiotensin-II induced mouse model of dissecting abdominal aortic aneurysms

K Genovese, MJ Collins, YU Lee… - Cardiovascular …, 2012 - Springer
Abdominal aortic aneurysms are focal dilatations of the aorta; they typically progress to
rupture, which is responsible for increasing morbidity and mortality in our aging society. It is …

[HTML][HTML] Multi-modality image-based computational analysis of haemodynamics in aortic dissection

D Dillon-Murphy, A Noorani, D Nordsletten… - … and modeling in …, 2016 - Springer
Aortic dissection is a disease whereby an injury in the wall of the aorta leads to the creation
of a true lumen and a false lumen separated by an intimal flap which may contain multiple …

Structural modeling reveals microstructure-strength relationship for human ascending thoracic aorta

JR Thunes, JA Phillippi, TG Gleason, DA Vorp… - Journal of …, 2018 - Elsevier
High lethality of aortic dissection necessitates accurate predictive metrics for dissection risk
assessment. The not infrequent incidence of dissection at aortic diameters< 5.5 cm, the …

[HTML][HTML] Hemodynamic effects of entry and exit tear size in aortic dissection evaluated with in vitro magnetic resonance imaging and fluid–structure interaction …

J Zimmermann, K Bäumler, M Loecher, TE Cork… - Scientific Reports, 2023 - nature.com
Understanding the complex interplay between morphologic and hemodynamic features in
aortic dissection is critical for risk stratification and for the development of individualized …

[HTML][HTML] Comparative analysis of patient-specific aortic dissections through computational fluid dynamics suggests increased likelihood of degeneration in partially …

S Moretti, F Tauro, M Orrico, N Mangialardi, AL Facci - Bioengineering, 2023 - mdpi.com
Aortic dissection is a life-threatening vascular disease associated with high rates of
morbidity and mortality, especially in medically underserved communities. Understanding …