Introduction. Despite the rapid development of neuroimaging techniques, the diagnosis of
amyotrophic lateral sclerosis (ALS) remains a significant challenge. Magnetic resonance …

Diffusion tensor imaging (DTI) for assessing ALS-associated white matter alterations has still
not reached the level of a neuroimaging biomarker. Since large-scale multicentre DTI …

RATIONALE AND OBJECTIVES: A number of studies have reported decreases in fractional
anistropy (FA) in amyotrophic lateral sclerosis using diffusion tensor imaging (DTI). The …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. However, no reliable
biomarkers have been identified to represent the clinical status. This study aimed to …

Objective To compare the results of magnetic resonance spectroscopy (MRS) and diffusion
tensor imaging (DTI) in amyotrophic lateral sclerosis (ALS) patients. Methods Nineteen ALS …

Purpose This paper aims to analyze the contribution of mean diffusivity (MD), axial diffusivity
(AD), and radial diffusivity (RD) in the detection of microstructural abnormalities in …

Rationale and Objectives There have been a large number of case-control studies using
diffusion tensor imaging (DTI) in amyotrophic lateral sclerosis (ALS). The objective of this …

Amyotrophic lateral sclerosis is a progressive neurodegenerative disease that affects upper
and lower motor neurons. Observational and intervention studies can be tracked using …

Purpose Diagnosis of amyotrophic lateral sclerosis (ALS) can be difficult from clinical
symptoms alone. Diffusion tensor imaging (DTI) has been suggested as an adjunct …

Amyotrophic lateral sclerosis (ALS) is a fatal progressive central nervous system disorder
affecting the upper and lower motor neurons. It is important to study the features of the …