Targeting cancer-related inflammation with non-steroidal anti-inflammatory drugs: Perspectives in pharmacogenomics
H Lai, Y Liu, J Wu, J Cai, H Jie, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Inflammatory processes are essential for innate immunity and contribute to carcinogenesis
in various malignancies, such as colorectal cancer, esophageal cancer and lung cancer …
in various malignancies, such as colorectal cancer, esophageal cancer and lung cancer …
Anti-inflammatory drugs as anticancer agents
S Zappavigna, AM Cossu, A Grimaldi… - International journal of …, 2020 - mdpi.com
Inflammation is strictly associated with cancer and plays a key role in tumor development
and progression. Several epidemiological studies have demonstrated that inflammation can …
and progression. Several epidemiological studies have demonstrated that inflammation can …
Molecular link mechanisms between inflammation and cancer
DB Vendramini-Costa… - Current pharmaceutical …, 2012 - ingentaconnect.com
Inflammation is part of the body's response to internal and external environmental stimuli
that normally eliminate the aggressor agent and restore the tissue physiology. However …
that normally eliminate the aggressor agent and restore the tissue physiology. However …
Small Molecules as Anti‐inflammatory Agents: Molecular Mechanisms and Heterocycles as Inhibitors of Signaling Pathways
NJ Basha - ChemistrySelect, 2023 - Wiley Online Library
Cancer and inflammation interlink with many pathways. Millions of people died because of
these two disorders. Major pathways that cause both inflammation and cancer are STAT3 …
these two disorders. Major pathways that cause both inflammation and cancer are STAT3 …
Role of nonsteroidal anti‐inflammatory drugs (NSAIDs) in cancer prevention and cancer promotion
RSY Wong - Advances in Pharmacological and Pharmaceutical …, 2019 - Wiley Online Library
The nonsteroidal anti‐inflammatory drugs (NSAIDs) are commonly prescribed by medical
practitioners in many clinical conditions for the symptomatic treatment of pain and fever. Due …
practitioners in many clinical conditions for the symptomatic treatment of pain and fever. Due …
[HTML][HTML] COX-independent mechanisms of cancer chemoprevention by anti-inflammatory drugs
E Gurpinar, WE Grizzle, GA Piazza - Frontiers in oncology, 2013 - frontiersin.org
Epidemiological and clinical studies suggest that non-steroidal anti-inflammatory drugs
(NSAIDs), including cyclooxygenase (COX)-2 selective inhibitors, reduce the risk of …
(NSAIDs), including cyclooxygenase (COX)-2 selective inhibitors, reduce the risk of …
NSAIDs and cancer resolution: new paradigms beyond cyclooxygenase
OR Kolawole, K Kashfi - International journal of molecular sciences, 2022 - mdpi.com
Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …
self-limiting, which returns the body to a state of homeostasis. However, unresolved …
Anti-tumor activity of non-steroidal anti-inflammatory drugs: cyclooxygenase-independent targets
JL Liggett, X Zhang, TE Eling, SJ Baek - Cancer letters, 2014 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are used extensively for analgesic and
antipyretic treatments. In addition, NSAIDs reduce the risk and mortality to several cancers …
antipyretic treatments. In addition, NSAIDs reduce the risk and mortality to several cancers …
Research advances in the intervention of inflammation and cancer by active ingredients of traditional Chinese medicine
Y Huang, T Cai, X Xia, Y Cai… - Journal of Pharmacy & …, 2016 - journals.library.ualberta.ca
A large body of evidence has shown that inflammation and cancer are strongly related. Thus
anti-inflammatory agents have been investigated for cancer prevention and treatment in …
anti-inflammatory agents have been investigated for cancer prevention and treatment in …
A review of gene-drug interactions for nonsteroidal anti-inflammatory drug use in preventing colorectal neoplasia
JT Cross, EM Poole, CM Ulrich - The pharmacogenomics journal, 2008 - nature.com
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to be effective
chemopreventive agents for colorectal neoplasia. Polymorphisms in NSAID targets or …
chemopreventive agents for colorectal neoplasia. Polymorphisms in NSAID targets or …