Dilated cardiomyopathy: the complexity of a diverse genetic architecture
Remarkable progress has been made in understanding the genetic basis of dilated
cardiomyopathy (DCM). Rare variants in> 30 genes, some also involved in other …
cardiomyopathy (DCM). Rare variants in> 30 genes, some also involved in other …
Genetic mutations and mechanisms in dilated cardiomyopathy
EM McNally, JR Golbus… - The Journal of clinical …, 2013 - Am Soc Clin Investig
Genetic mutations account for a significant percentage of cardiomyopathies, which are a
leading cause of congestive heart failure. In hypertrophic cardiomyopathy (HCM), cardiac …
leading cause of congestive heart failure. In hypertrophic cardiomyopathy (HCM), cardiac …
The complex and diverse genetic architecture of dilated cardiomyopathy
RE Hershberger, J Cowan, E Jordan… - Circulation …, 2021 - Am Heart Assoc
Our insight into the diverse and complex nature of dilated cardiomyopathy (DCM) genetic
architecture continues to evolve rapidly. The foundations of DCM genetics rest on marked …
architecture continues to evolve rapidly. The foundations of DCM genetics rest on marked …
[HTML][HTML] Clinical and genetic issues in dilated cardiomyopathy: a review for genetics professionals
RE Hershberger, A Morales, JD Siegfried - Genetics in Medicine, 2010 - Elsevier
Dilated cardiomyopathy (DCM), usually diagnosed as idiopathic dilated cardiomyopathy
(IDC), has been shown to have a familial basis in 20–35% of cases. Genetic studies in …
(IDC), has been shown to have a familial basis in 20–35% of cases. Genetic studies in …
Familial dilated cardiomyopathy
Advances in human genome sequencing have re-invigorated genetics studies of dilated
cardiomyopathy (DCM), facilitating genetic testing and clinical applications. With a range of …
cardiomyopathy (DCM), facilitating genetic testing and clinical applications. With a range of …
[HTML][HTML] Dilated cardiomyopathy overview
RE Hershberger, E Jordan - 2022 - europepmc.org
Dilated Cardiomyopathy Overview - Abstract - Europe PMC Sign in | Create an account https://orcid.org
Europe PMC Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter …
Europe PMC Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter …
Genetics of dilated cardiomyopathy
D Fatkin, R Otway, Z Richmond - Heart Failure Clinics, 2010 - heartfailure.theclinics.com
Dilated cardiomyopathy (DCM) is a myocardial disorder defined by ventricular chamber
enlargement and systolic dysfunction that can result in progressive heart failure …
enlargement and systolic dysfunction that can result in progressive heart failure …
[HTML][HTML] Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy
AE Minoche, C Horvat, R Johnson, V Gayevskiy… - Genetics in …, 2019 - Elsevier
Purpose We evaluated genome sequencing (GS) as an alternative to multigene panel
sequencing (PS) for genetic testing in dilated cardiomyopathy (DCM). Methods Forty-two …
sequencing (PS) for genetic testing in dilated cardiomyopathy (DCM). Methods Forty-two …
Dilated cardiomyopathy: genetic determinants and mechanisms
EM McNally, L Mestroni - Circulation research, 2017 - Am Heart Assoc
Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …
the large number of genes and alleles attributed to DCM, comprehensive genetic testing …
Guidelines for the diagnosis and management of familial dilated cardiomyopathy
D Fatkin… - Heart, Lung and …, 2011 - Elsevier
Dilated cardiomyopathy (DCM) is a myocardial disorder that is a major cause of heart failure
and death. Recent data indicate that genetic factors are important in the pathogenesis of …
and death. Recent data indicate that genetic factors are important in the pathogenesis of …