Genetics of dilated cardiomyopathy
S Kärkkäinen, K Peuhkurinen - Annals of medicine, 2007 - Taylor & Francis
Dilated cardiomyopathy (DCM) is a myocardial disease characterized by dilatation and
impaired systolic function of the left or both ventricles. The etiology of DCM is multifactorial …
impaired systolic function of the left or both ventricles. The etiology of DCM is multifactorial …
Evidence-based assessment of genes in dilated cardiomyopathy
E Jordan, L Peterson, T Ai, B Asatryan, L Bronicki… - Circulation, 2021 - Am Heart Assoc
Background: Each of the cardiomyopathies, classically categorized as hypertrophic
cardiomyopathy, dilated cardiomyopathy (DCM), and arrhythmogenic right ventricular …
cardiomyopathy, dilated cardiomyopathy (DCM), and arrhythmogenic right ventricular …
Reevaluating the genetic contribution of monogenic dilated cardiomyopathy
F Mazzarotto, U Tayal, RJ Buchan, W Midwinter… - Circulation, 2020 - Am Heart Assoc
Background: Dilated cardiomyopathy (DCM) is genetically heterogeneous, with> 100
purported disease genes tested in clinical laboratories. However, many genes were …
purported disease genes tested in clinical laboratories. However, many genes were …
Investigation of a family with autosomal dominant dilated cardiomyopathy defines a novel locus on chromosome 2q14-q22
M Jung, I Poepping, A Perrot, AE Ellmer… - The American Journal of …, 1999 - cell.com
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and the most frequent
indication for heart transplantation in young patients. Probably> 25% of DCM cases are of …
indication for heart transplantation in young patients. Probably> 25% of DCM cases are of …
Atlas of the clinical genetics of human dilated cardiomyopathy
Aim Numerous genes are known to cause dilated cardiomyopathy (DCM). However, until
now technological limitations have hindered elucidation of the contribution of all clinically …
now technological limitations have hindered elucidation of the contribution of all clinically …
Frequency, penetrance, and variable expressivity of dilated cardiomyopathy–associated putative pathogenic gene variants in UK Biobank participants
Background: There is a paucity of data regarding the phenotype of dilated cardiomyopathy
(DCM) gene variants in the general population. We aimed to determine the frequency and …
(DCM) gene variants in the general population. We aimed to determine the frequency and …
Implications of genetic testing in dilated cardiomyopathy
JAJ Verdonschot, MR Hazebroek… - Circulation: Genomic …, 2020 - Am Heart Assoc
Background: Genetic analysis is a first-tier test in dilated cardiomyopathy (DCM). Electrical
phenotypes are common in genetic DCM, but their exact contribution to the clinical course …
phenotypes are common in genetic DCM, but their exact contribution to the clinical course …
Dilated cardiomyopathy in the era of precision medicine: latest concepts and developments
N Orphanou, E Papatheodorou, A Anastasakis - Heart failure reviews, 2022 - Springer
Dilated cardiomyopathy (DCM) is an umbrella term entailing a wide variety of genetic and
non-genetic etiologies, leading to left ventricular systolic dysfunction and dilatation, not …
non-genetic etiologies, leading to left ventricular systolic dysfunction and dilatation, not …
Genetic causes of dilated cardiomyopathy
L Mestroni, F Brun, A Spezzacatene, G Sinagra… - Progress in pediatric …, 2014 - Elsevier
Dilated cardiomyopathy is a disease of the myocardium characterized by left ventricular
dilatation and/or dysfunction, affecting both adult and pediatric populations. Almost half of …
dilatation and/or dysfunction, affecting both adult and pediatric populations. Almost half of …
Clinical and genetic issues in familial dilated cardiomyopathy
EL Burkett, RE Hershberger - Journal of the American College of …, 2005 - jacc.org
Idiopathic dilated cardiomyopathy (IDC) is characterized by left ventricular dilatation and
systolic dysfunction after known causes have been excluded. Idiopathic dilated …
systolic dysfunction after known causes have been excluded. Idiopathic dilated …