Cryptococcosis is a common opportunistic fungal infection that often disseminates into the
central nervous system, leading to meningitis. Production of melanin pigments during …

Melanin is an antioxidant polyphenol pigment required for the pathogenicity of many fungal
pathogens, but comprehensive regulatory mechanisms remain unidentified. In this study, we …

The fungal human pathogen Cryptococcus neoformans undergoes melanization in
response to nutrient starvation and exposure to exogenous melanin precursors …

The ability to produce melanin is a key virulence factor in many fungal pathogens including
the human basidiomycete pathogen Cryptococcus neoformans, a major cause of life …

The pathogenic fungus Cryptococcus neoformans produces melanin within its cell wall for
infection and resistance against external stresses such as exposure to UV, temperature …

Background The adaptation of pathogenic fungi to the host environment via large-scale
genomic changes is a poorly characterized phenomenon. Cryptococcus neoformans is the …

The Cryptococcus neoformans species complex (CNSC) is a common opportunistic human
fungal pathogen and the most frequent cause of fungal meningitis. There are three major …

Cryptococcus neoformans and Cryptococcus gattii are two species complexes in the large
fungal genus Cryptococcus and are responsible for potentially lethal disseminated …

Cryptococcus neoformans, a spore-producing pathogenic yeast, affects
immunocompromised individuals causing meningoencephalitis. Once C. neoformans is …

Cryptococcus spp. are human pathogens that cause 181,000 deaths per year. In this work,
we systematically investigated the virulence attributes of Cryptococcus spp. clinical isolates …