Grape seed polyphenols ameliorated dextran sulfate sodium-induced colitis via suppression of inflammation and apoptosis

Y Wang, Y Wang, W Shen, Y Wang, Y Cao… - Pharmacology, 2020 - karger.com
Background: Ulcerative colitis (UC) is an inflammatory bowel disease. Its onset is typically
gradual, usually followed by periods of spontaneous remission and subsequent relapses …

Grape seed extract reduces the severity of selected disease markers in the proximal colon of dextran sulphate sodium-induced colitis in rats

KY Cheah, SEP Bastian, TMV Acott… - Digestive diseases and …, 2013 - Springer
Background Grape seed extract (GSE) constitutes a rich source of procyanidins. GSE has
been demonstrated to exert encouraging anti-inflammatory and anti-ulcer properties in …

Polyphenol‐rich grape pomace extracts protect against dextran sulfate sodium‐induced colitis in rats

A Boussenna, J Cholet… - Journal of the …, 2016 - Wiley Online Library
BACKGROUND Several studies have reported that polyphenols may exert beneficial effects
on inflammatory bowel disease. This study aimed to evaluate the effects of preventive …

Protective effects of grape seed proanthocyanidin extract in preventing dss induced ulcerative colitis based on pharmacodynamic, pharmacokinetic and tissue …

X Wang, S Quan, J Li, Y Liu, H Sun… - Current drug …, 2022 - ingentaconnect.com
Background: Based on pharmacodynamic, pharmacokinetic and tissue distribution studies,
we explored the potential effect of grape seed proanthocyanidin extract (GSPE) on dextran …

Grape seed proanthocyanidin extract ameliorates dextran sulfate sodium-induced colitis through intestinal barrier improvement, oxidative stress reduction, and …

K Sheng, G Zhang, M Sun, S He, X Kong, J Wang… - Food & function, 2020 - pubs.rsc.org
It is widely believed that grape seed proanthocyanidin extract (GSPE) exerts antioxidant and
anti-inflammatory effects. Dietary supplementation with GSPE has been reported to alleviate …

Safranal alleviates dextran sulfate sodium-induced colitis and suppresses macrophage-mediated inflammation

P Lertnimitphun, Y Jiang, N Kim, W Fu… - Frontiers in …, 2019 - frontiersin.org
Introduction: Crocus sativus (saffron) is widely used in China, Iran, and India for dyeing and
as a food additive and medicinal plant. Safranal, as one of the main constituents of saffron, is …

Resveratrol alleviates dextran sulfate sodium-induced acute ulcerative colitis in mice by mediating PI3K/Akt/VEGFA pathway

F Zhu, J Zheng, F Xu, Y Xi, J Chen, X Xu - Frontiers in pharmacology, 2021 - frontiersin.org
Ulcerative colitis (UC) is a chronic inflammatory disease that affects the colon, and its
incidence is on the rise worldwide. Resveratrol (RSV), a polyphenolic compound, was …

Dietary tangeretin alleviated dextran sulfate sodium-induced colitis in mice via inhibiting inflammatory response, restoring intestinal barrier function, and modulating …

B Chen, J Luo, Y Han, H Du, J Liu, W He… - Journal of Agricultural …, 2021 - ACS Publications
In this study, the preventive effect of tangeretin (TAN), a natural flavonoid derivative from
citrus fruits, on the dextran sulfate sodium (DSS)-induced colitis in mice was evaluated. Our …

Muscadine Grape (Vitis rotundifolia) or Wine Phytochemicals Reduce Intestinal Inflammation in Mice with Dextran Sulfate Sodium-Induced Colitis

R Li, MH Kim, AK Sandhu, C Gao… - Journal of agricultural and …, 2017 - ACS Publications
The objective of this study was to determine the anti-inflammatory effects of phytochemical
extracts from muscadine grapes or wine on dextran sulfate sodium (DSS)-induced colitis in …

Eugenol alleviates dextran sulfate sodium-induced colitis independent of intestinal microbiota in mice

S Chen, X Wu, S Tang, J Yin, Z Song… - Journal of Agricultural …, 2021 - ACS Publications
The present study investigated the effect of eugenol (EUG) on dextran sulfate sodium (DSS)-
induced colitis and explored the underlying mechanisms. C57BL/6 mice were …