High IFN-γ/IL-10 expression ratio and increased frequency of persistent human T-cell lymphotropic virus type 1-infected clones are associated with human T-cell …

OM Espíndola, LC Oliveira, P Ferreira, ACCB Leite… - Intervirology, 2015 - karger.com
Background/Aims: Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that
causes a persistent infection, and only 0.5-5% of infected individuals will develop HTLV-1 …

Human T lymphotropic virus type 1 (HTLV-1) proviral load induces activation of T-lymphocytes in asymptomatic carriers

R Coutinho, MFR Grassi, AB Korngold… - BMC Infectious …, 2014 - Springer
Background High HTLV-1 proviral load (PVL) is mainly found in infected individuals with
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However one third …

Proviral load and immune markers associated with human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in …

I Best, V Adaui, K Verdonck, E Gonzalez… - Clinical & …, 2006 - academic.oup.com
Human T-lymphotropic virus type 1 (HTLV-1) is the aetiological agent of HTLV-1-associated
myelopathy/tropical spastic paraparesis (HAM/TSP). The objective of this study is to identify …

Establishing phenotypic features associated with morbidity in human T-cell lymphotropic virus type 1 infection

GEA Brito-Melo, JG Souza… - Clinical and Vaccine …, 2004 - Am Soc Microbiol
The human T-cell lymphotropic virus type 1 (HTLV-1) is the causative agent of HTLV-1-
associated myelopathy/tropical spastic paraparesis (HT). Although it is widely believed that …

Cytokine profile and proviral load among Japanese immigrants and non-Japanese infected with HTLV-1 in a non-endemic area of Brazil

JA Domingos, LS Soares, LM Bandeira, CM Bonin… - PLoS …, 2017 - journals.plos.org
The lifetime risk of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
development differs among ethnic groups. To better understand these differences, this …

Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP)

PD Burbelo, E Meoli, HP Leahy, J Graham, K Yao… - Retrovirology, 2008 - Springer
Background HTLV-I is the causal agent of adult T cell leukemia (ATLL) and HTLV-I-
associated myelopathy/tropical spastic paraparesis (HAM/TSP). Biomarkers are needed to …

Evaluation of host genetic and viral factors as surrogate markers for HTLV‐1‐associated myelopathy/tropical spastic paraparesis in Peruvian HTLV‐1‐infected …

M Talledo, G Lopez, JR Huyghe… - Journal of medical …, 2010 - Wiley Online Library
Human T‐lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a complication that affects up to 5% of HTLV‐1‐infected …

Imbalanced IL10/TGF-β production by regulatory T-lymphocytes in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis

LL Gois, B Ribeiro-Soares, CG Regis-Silva… - BMC Infectious …, 2024 - Springer
Background Human T-cell lymphotropic virus type 1 (HTLV-1), also denominated Human T-
cell leukemia virus-1, induces immune activation and secretion of proinflammatory …

IFN‐γ production in response to Tax 161–233, and frequency of CD4+ Foxp3+ and Lin HLA‐DRhigh CD123+ cells, discriminate HAM/TSP patients from …

I Best, G López, K Verdonck, E González… - …, 2009 - Wiley Online Library
Human T‐lymphotropic virus 1 (HTLV‐1) can cause HTLV‐1‐associated myelopathy/tropical
spastic paraparesis (HAM/TSP). The objective of this study was to gain insight into the …

Increased HTLV Type 1 Tax Specific CD8+ Cells in HTLV Type 1-Asociated Myelopathy/Tropical Spastic Paraparesis: Correlation with HTLV Type 1 Proviral Load

R Kubota, M Nagai, T Kawanishi, M Osame… - AIDS research and …, 2000 - liebertpub.com
Less than 1% of individuals infected with the human T lymphotropic virus type 1 (HTLV-1)
develop an inflammatory neurological disorder, termed HTLV-1-associated …