Identification of peptides and their linked amino acids from chemically cross-linked protein
complexes with bifunctional N-hydroxysuccinimidyl (NHS) esters can reveal interacting …

RATIONALE Chemical cross‐linking in combination with a mass spectrometric analysis of
the created cross‐linked products is an area of growing interest for deriving low‐resolution …

Structural mass spectrometry (MS) is a field with growing applicability for addressing
complex biophysical questions regarding proteins and protein complexes. One of the major …

Graphical Abstract Abstract Chemical cross-linking coupled with mass spectrometry (CXMS)
identifies protein residues that are close in space, and has been increasingly used for …

Chemical cross-linking in combination with mass spectrometry (XL-MS) has emerged as a
useful method for structural elucidation of proteins and protein complexes. Due to the low …

Cross-linking mass spectrometry draws structural information from covalently linked peptide
pairs. When these links do not match to previous structural models, they may indicate …

Motivation Cross-linking mass spectrometry has made remarkable advancements in the
high-throughput characterization of protein structures and interactions. The resulting pairs of …

Such cross-linked biomolecules and/or biomolecular com plexes, a method for cleavage
and reduction of Such cross linked biomolecules and/or biomolecular complexes, a method …

Chemical crosslinking can identify the neighborhood relationships between specific amino-
acid residues in proteins. The interpretation of crosslinking data is typically performed using …

The development of a peptide retention prediction model for strong cation exchange (SCX)
separation on a Polysulfoethyl A column is reported. Off-line 2D LC-MS/MS analysis (SCX …